Overview

  • Product name

  • Description

    Rabbit polyclonal to NUDT16
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-P, ICC/IFmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant fragment corresponding to Human NUDT16.
    Sequence:

    VERPDYRSSHAGSRPRVVAHFYAKSL


    Database link: Q96DE0

  • Positive control

    • Human appendix tissue and MCF7 cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab204739 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/20 - 1/50. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
ICC/IF Use a concentration of 1 - 4 µg/ml.

Fixation/Permeabilization: PFA/Triton X-100

Target

  • Function

    RNA-decapping enzyme that binds specifically to U8 snoRNA. Part of the U8 snoRNP complex that is required for the accumulation of mature 5.8S and 28S rRNA. Has diphosphatase activity and removes m7G and m227G caps from U8 snoRNA. Has broad substrate specificity with manganese or cobalt as cofactor and can act on various RNA species (in vitro).
  • Sequence similarities

    Belongs to the Nudix hydrolase family.
    Contains 1 nudix hydrolase domain.
  • Cellular localization

    Nucleus > nucleolus. Nucleus > nucleoplasm. Predominantly localized in nucleolus, and in a minor proportion in distinct foci in the nucleoplasm.
  • Information by UniProt
  • Database links

  • Alternative names

    • FLJ31265 antibody
    • FLJ34034 antibody
    • FLJ36248 antibody
    • Nucleoside diphosphate-linked moiety X motif 16 antibody
    • NUD16_HUMAN antibody
    • Nudix (nucleoside diphosphate linked moiety X) type motif 16 antibody
    • Nudix motif 16 antibody
    • NUDT 16 antibody
    • NUDT16 antibody
    • U8 snoRNA-binding protein H29K antibody
    • U8 snoRNA-decapping enzyme antibody
    see all

Images

  • Immunohistochemical analysis of paraffin-embedded Human appendix tissue labeling NUDT16 with ab204739 at a dilution of 1/20.

  • Immunofluorescent analysis of MCF7 cells labeling NUDT16 with ab204739 at 4 µg/mL.

References

ab204739 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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