Anti-Nurr1 antibody (ab176184)
- Datasheet
- References
- Protocols
Overview
-
Product nameAnti-Nurr1 antibody
See all Nurr1 primary antibodies -
DescriptionRabbit polyclonal to Nurr1
-
Host speciesRabbit
-
Tested applicationsSuitable for: WBmore details
-
Species reactivityReacts with: Human
-
Immunogen
Synthetic peptide within Human Nurr1 aa 566-591. The exact sequence is proprietary. The selected peptide was post-synthetically modified to achieve highest antigenicity before coupling to carrier protein using hetero bifunctional cross linker.
Sequence:CTQGLQRIFYLKLEDLVPPPAIIDKL
Database link: P43354
Properties
-
FormLiquid
-
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
-
Storage bufferPreservative: 0.02% Sodium azide
-
Concentration information loading... -
PurityImmunogen affinity purified
-
ClonalityPolyclonal
-
IsotypeIgG
-
Research areas
Associated products
-
Compatible Secondaries
-
Isotype control
Applications
Our Abpromise guarantee covers the use of ab176184 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB | 1/500. Detects a band of approximately 75 kDa (predicted molecular weight: 67 kDa). |
Target
-
FunctionTranscriptional regulator which is important for the differentiation and maintenance of meso-diencephalic dopaminergic (mdDA) neurons during development. It is crucial for expression of a set of genes such as SLC6A3, SLC18A2, TH and DRD2 which are essential for development of mdDA neurons.
-
Tissue specificityExpressed in a number of cell lines of T-cell, B-cell and fibroblast origin. Strong expression in brain tissue.
-
Sequence similaritiesBelongs to the nuclear hormone receptor family. NR4 subfamily.
Contains 1 nuclear receptor DNA-binding domain. -
Developmental stageRapidly and only very transiently expressed after cell activation, during the G0-G1 transition of the cell cycle.
-
Cellular localizationNucleus.
- Information by UniProt
-
Database links
- Entrez Gene: 4929 Human
- Omim: 601828 Human
- SwissProt: P43354 Human
- Unigene: 563344 Human
-
Alternative names
- HZF 3 antibody
- HZF3 antibody
- Immediate-early response protein NOT antibody
see all
Protocols
Datasheets and documents
References
ab176184 has not yet been referenced specifically in any publications.
