Overview

  • Product name
    Anti-Nurr1 antibody
    See all Nurr1 primary antibodies
  • Description
    Rabbit polyclonal to Nurr1
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide within Human Nurr1 aa 566-591. The exact sequence is proprietary. The selected peptide was post-synthetically modified to achieve highest antigenicity before coupling to carrier protein using hetero bifunctional cross linker.
    Sequence:

    CTQGLQRIFYLKLEDLVPPPAIIDKL


    Database link: P43354

    Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI

Properties

Applications

Our Abpromise guarantee covers the use of ab176184 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500. Detects a band of approximately 75 kDa (predicted molecular weight: 67 kDa).

Target

  • Function
    Transcriptional regulator which is important for the differentiation and maintenance of meso-diencephalic dopaminergic (mdDA) neurons during development. It is crucial for expression of a set of genes such as SLC6A3, SLC18A2, TH and DRD2 which are essential for development of mdDA neurons.
  • Tissue specificity
    Expressed in a number of cell lines of T-cell, B-cell and fibroblast origin. Strong expression in brain tissue.
  • Sequence similarities
    Belongs to the nuclear hormone receptor family. NR4 subfamily.
    Contains 1 nuclear receptor DNA-binding domain.
  • Developmental stage
    Rapidly and only very transiently expressed after cell activation, during the G0-G1 transition of the cell cycle.
  • Cellular localization
    Nucleus.
  • Information by UniProt
  • Database links
    • Alternative names
      • HZF 3 antibody
      • HZF3 antibody
      • Immediate-early response protein NOT antibody
      • Intermediate early receptor protein antibody
      • NGFI B/nur77 beta type transcription factor homolog antibody
      • NOT antibody
      • Nr4a2 antibody
      • NR4A2_HUMAN antibody
      • nuclear receptor of T cells antibody
      • nuclear receptor related 1 antibody
      • Nuclear receptor subfamily 4 group A member 2 antibody
      • Nur related protein 1 homolog antibody
      • nur related protein-1, human homolog of antibody
      • Nurr 1 antibody
      • Orphan nuclear receptor NR4A2 antibody
      • Orphan nuclear receptor NURR1 antibody
      • RNR 1 antibody
      • RNR1 antibody
      • T cell nuclear receptor NOT antibody
      • T-cell nuclear receptor NOT antibody
      • TINUR antibody
      • Transcriptionally inducible nuclear receptor antibody
      • Transcriptionally inducible nuclear receptor related antibody
      • Transcriptionally inducible nuclear receptor related 1 antibody
      • Transcriptionally-inducible nuclear receptor antibody
      see all

    References

    ab176184 has not yet been referenced specifically in any publications.

    Publishing research using ab176184? Please let us know so that we can cite the reference in this datasheet.

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