Anti-Nurr1 antibody (ab176184)
- Datasheet
- References
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Overview
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Product nameAnti-Nurr1 antibody
See all Nurr1 primary antibodies -
DescriptionRabbit polyclonal to Nurr1
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Host speciesRabbit
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Tested applicationsSuitable for: WBmore details
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Species reactivityReacts with: Human
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Immunogen
Synthetic peptide within Human Nurr1 aa 566-591. The exact sequence is proprietary. The selected peptide was post-synthetically modified to achieve highest antigenicity before coupling to carrier protein using hetero bifunctional cross linker.
Sequence:CTQGLQRIFYLKLEDLVPPPAIIDKL
Database link: P43354
Properties
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FormLiquid
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
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Storage bufferPreservative: 0.02% Sodium azide
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Concentration information loading... -
PurityImmunogen affinity purified
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ClonalityPolyclonal
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IsotypeIgG
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Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
Our Abpromise guarantee covers the use of ab176184 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB | 1/500. Detects a band of approximately 75 kDa (predicted molecular weight: 67 kDa). |
Target
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FunctionTranscriptional regulator which is important for the differentiation and maintenance of meso-diencephalic dopaminergic (mdDA) neurons during development. It is crucial for expression of a set of genes such as SLC6A3, SLC18A2, TH and DRD2 which are essential for development of mdDA neurons.
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Tissue specificityExpressed in a number of cell lines of T-cell, B-cell and fibroblast origin. Strong expression in brain tissue.
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Sequence similaritiesBelongs to the nuclear hormone receptor family. NR4 subfamily.
Contains 1 nuclear receptor DNA-binding domain. -
Developmental stageRapidly and only very transiently expressed after cell activation, during the G0-G1 transition of the cell cycle.
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Cellular localizationNucleus.
- Information by UniProt
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Database links
- Entrez Gene: 4929 Human
- Omim: 601828 Human
- SwissProt: P43354 Human
- Unigene: 563344 Human
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Alternative names
- HZF 3 antibody
- HZF3 antibody
- Immediate-early response protein NOT antibody
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Datasheets and documents
Protocols
References
ab176184 has not yet been referenced specifically in any publications.
