Product nameO-Phospho-L-tyrosine, Tyrosine-phosphorylation reagent
Useful reagent in the study of tyrosine-phosphorylation, which has been linked with the malignant transformation of cells by some RNA tumour viruses.
Soluble in water in pH 7.
Chemical nameL-3-(4-Hydroxyphenyl)alanine 4'-phosphate
Storage instructionsStore at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
This product has been referenced in:
- Afonso A et al. Purification of pre-miR-29 by a new O-phospho-l-tyrosine affinity chromatographic strategy optimized using design of experiments. J Chromatogr A 1343:119-27 (2014). Read more (PubMed: 24751555) »
- Ullah AH et al. Kinetic characterization of O-phospho-L-tyrosine phosphohydrolase activity of two fungal phytases. J Agric Food Chem 56:7467-71 (2008). Read more (PubMed: 18627164) »
- Mishra S & Hamburger AW Association of inhibition of cell growth by O-phospho-L-tyrosine with decreased tyrosine phosphorylation. Cancer Lett 102:65-71 (1996). Read more (PubMed: 8603380) »
- Mishra S & Hamburger AW O-phospho-L-tyrosine inhibits cellular growth by activating protein tyrosine phosphatases. Cancer Res 53:557-63 (1993). Read more (PubMed: 7678776) »