Anti-OAS2 antibody (ab195968)
Key features and details
- Goat polyclonal to OAS2
- Suitable for: IHC-P, WB
- Reacts with: Human
- Isotype: IgG
Overview
-
Product name
Anti-OAS2 antibody
See all OAS2 primary antibodies -
Description
Goat polyclonal to OAS2 -
Host species
Goat -
Tested applications
Suitable for: IHC-P, WBmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Chimpanzee, Gorilla -
Immunogen
Synthetic peptide corresponding to Human OAS2 aa 350-450 (internal sequence). (NP_058197.2).
Database link: P29728 -
Positive control
- Human breast tissue; Daudi, K562 and Jurkat cell lysates.
-
General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
-
Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 99% Tris buffered saline, 0.5% BSA -
Concentration information loading...
-
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
-
Compatible Secondaries
-
Isotype control
-
Positive Controls
-
Recombinant Protein
-
Related Products
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab195968 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
IHC-P |
Use a concentration of 5 µg/ml.
|
|
WB |
Use a concentration of 0.3 - 1 µg/ml. Detects a band of approximately 70 kDa (predicted molecular weight: 82, 79 kDa).
|
Notes |
---|
IHC-P
Use a concentration of 5 µg/ml. |
WB
Use a concentration of 0.3 - 1 µg/ml. Detects a band of approximately 70 kDa (predicted molecular weight: 82, 79 kDa). |
Target
-
Function
May play a role in mediating resistance to virus infection, control of cell growth, differentiation, and apoptosis. -
Sequence similarities
Belongs to the 2-5A synthase family. -
Cellular localization
Mitochondrion. Nucleus. Microsome. Endoplasmic reticulum. Associated with different subcellular fractions such as mitochondrial, nuclear, and rough/smooth microsomal fractions. - Information by UniProt
-
Database links
- Entrez Gene: 4939 Human
- Omim: 603350 Human
- SwissProt: P29728 Human
- Unigene: 414332 Human
-
Alternative names
- (2-5'')oligo(A) synthase 2 antibody
- (2-5')oligo(A) synthetase 2 antibody
- 2''-5''-oligoadenylate synthase 2 antibody
see all
Images
-
All lanes : Anti-OAS2 antibody (ab195968) at 0.3 µg/ml
Lane 1 : Daudi cell lysate (in RIPA buffer)
Lane 2 : Jurkat cell lysate (in RIPA buffer)
Lane 3 : K562 cell lysate (in RIPA buffer)
Lysates/proteins at 35 µg per lane.
Developed using the ECL technique.
Predicted band size: 82, 79 kDa
Observed band size: 70 kDa why is the actual band size different from the predicted?Primary incubation was 1 hour.
-
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human breast tissue labeling OAS2 with ab195968 at 5 µg/ml.
Protocols
Datasheets and documents
-
Datasheet download
References (1)
ab195968 has been referenced in 1 publication.
- Zhou H et al. Long noncoding RNA SATB1-AS1 contributes to the chemotherapy resistance through the microRNA-580/ 2'-5'-oligoadenylate synthetase 2 axis in acute myeloid leukemia. Bioengineered 12:6403-6417 (2021). PubMed: 34516354