Key features and details
- Rabbit polyclonal to OAS3
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
Product nameAnti-OAS3 antibody
See all OAS3 primary antibodies
DescriptionRabbit polyclonal to OAS3
Tested applicationsSuitable for: WB, IHC-Pmore details
Species reactivityReacts with: Human
Recombinant fragment, corresponding to a region within amino acids 87-393 of Human OAS3 (Uniprot ID: Q9Y6K5).
- A431 whole cell lysates; Human D54MG xenograft tissue.
Storage instructionsShipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferpH: 7.00
Preservative: 0.025% Proclin 300
Constituents: PBS, 1% BSA, 20% Glycerol
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab154270 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/3000. Predicted molecular weight: 121 kDa.|
|IHC-P||1/100 - 1/1000.|
FunctionMay play a role in mediating resistance to virus infection, control of cell growth, differentiation, and apoptosis. OAS3 synthesizes preferentially dimeric 2',5'-oligoadenylate molecules. GTP can be an alternative substrate.
Tissue specificityPresent at high level in placenta trophoblast.
Sequence similaritiesBelongs to the 2-5A synthase family.
- Information by UniProt
- (2-5'')oligo(A) synthase 3 antibody
- 2 5' oligo(A) synthetase 3 antibody
- 2 5'LIGO antibody
ab154270 has been referenced in 3 publications.
- Nogimori T et al. Dom34 mediates targeting of exogenous RNA in the antiviral OAS/RNase L pathway. Nucleic Acids Res 47:432-449 (2019). PubMed: 30395302
- Nogimori T et al. A novel method for stabilizing microRNA mimics. Biochem Biophys Res Commun 511:422-426 (2019). PubMed: 30799083
- Odon V et al. The role of ZAP and OAS3/RNAseL pathways in the attenuation of an RNA virus with elevated frequencies of CpG and UpA dinucleotides. Nucleic Acids Res 47:8061-8083 (2019). PubMed: 31276592