Key features and details
- Rabbit polyclonal to OASL - N-terminal
- Suitable for: ICC, ICC/IF, WB
- Reacts with: Mouse, Rat, Human
- Isotype: IgG
Product nameAnti-OASL antibody - N-terminal
See all OASL primary antibodies
DescriptionRabbit polyclonal to OASL - N-terminal
Tested applicationsSuitable for: ICC, ICC/IF, WBmore details
Species reactivityReacts with: Mouse, Rat, Human
Synthetic peptide corresponding to Human OASL. 17 amino acid peptide.
Database link: Q15646
- HepG2 cells; mouse bladder tissue lysate.
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We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.2
Preservative: 0.02% Sodium azide
Constituent: 99% PBS
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab191701 in the following tested applications.
|ICC||Use a concentration of 2.5 µg/ml.|
|ICC/IF||Use a concentration of 20 µg/ml.|
|WB||Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 59 kDa.|
FunctionDoes not have 2'-5'-OAS activity, but can bind double-stranded RNA. Displays antiviral activity against encephalomyocarditis virus (EMCV) and hepatitis C virus (HCV) via an alternative antiviral pathway independent of RNase L.
Tissue specificityExpressed in most tissues, with the highest levels in primary blood Leukocytes and other hematopoietic system tissues, colon, stomach and to some extent in testis.
Sequence similaritiesBelongs to the 2-5A synthase family.
Contains 2 ubiquitin-like domains.
DomainThe ubiquitin-like domains are essential for its antiviral activity.
Cellular localizationCytoplasm and Nucleus > nucleolus. Cytoplasm.
- Information by UniProt
- 2' 5' oligoadenylate synthetase like antibody
- 2''-5''-OAS-related protein antibody
- 2''-5''-OAS-RP antibody
ab191701 has not yet been referenced specifically in any publications.