Key features and details
- Rabbit polyclonal to OATP1B1
- Suitable for: ICC, WB
- Reacts with: Human
- Isotype: IgG
Product nameAnti-OATP1B1 antibody
See all OATP1B1 primary antibodies
DescriptionRabbit polyclonal to OATP1B1
This antibody is predicted to not cross-react with other SLCO1B proteins.
Tested applicationsSuitable for: ICC, WBmore details
Species reactivityReacts with: Human
Synthetic peptide within Human OATP1B1 aa 641-691. The exact sequence is proprietary. 14 amino acids long.
Database link: Q9Y6L6
- WB: Human liver tissue lysate. IF: Human liver tissue. ICC: HepG2 cells.
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.2
Preservative: 0.02% Sodium azide
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab254575 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|ICC||Use a concentration of 2.5 µg/ml.|
|WB||Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 76 kDa.|
|IF||Use a concentration of 20 µg/ml.|
FunctionMediates the Na(+)-independent uptake of organic anions such as pravastatin, taurocholate, methotrexate, dehydroepiandrosterone sulfate, 17-beta-glucuronosyl estradiol, estrone sulfate, prostaglandin E2, thromboxane B2, leukotriene C3, leukotriene E4, thyroxine and triiodothyronine. May play an important role in the clearance of bile acids and organic anions from the liver.
Tissue specificityHighly expressed in liver. Not detected in heart, brain, placenta, lung, skeletal muscle, kidney, pancreas, spleen, thymus, prostate, testis, ovary, small intestine, colon and leukocyte.
Sequence similaritiesBelongs to the organo anion transporter (TC 2.A.60) family.
Contains 1 Kazal-like domain.
Cellular localizationBasolateral cell membrane. Detected in basolateral membranes of hepatocytes.
- Information by UniProt
- Liver-specific organic anion transporter 1 antibody
- LST-1 antibody
- LST1 antibody
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab254575 has not yet been referenced specifically in any publications.