Overview

  • Product name

    Anti-OB Cadherin antibody [16G5]
    See all OB Cadherin primary antibodies
  • Description

    Mouse monoclonal [16G5] to OB Cadherin
  • Host species

    Mouse
  • Tested applications

    Suitable for: WB, ICC/IF, IPmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Extracellular Cadherin domain 1 of OB Cadherin fused to maltose binding protein (P55287).

Properties

Applications

Our Abpromise guarantee covers the use of ab151446 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100. Predicted molecular weight: 87 kDa.
ICC/IF Use at an assay dependent concentration.
IP Use at an assay dependent concentration.

Target

  • Function

    Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
  • Tissue specificity

    Expressed mainly in brain but also found in other tissues. Expressed in neuroblasts.
  • Involvement in disease

    Note=A chromosomal aberration involving CDH11 is a common genetic feature of aneurysmal bone cyst, a benign osseous neoplasm. Translocation t(16;17)(q22;p13) with USP6. The translocation generates a fusion gene in which the strong CDH11 promoter is fused to the entire USP6 coding sequence, resulting in USP6 transcriptional up-regulation.
  • Sequence similarities

    Contains 5 cadherin domains.
  • Cellular localization

    Cell membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • CAD11 antibody
    • CAD11_HUMAN antibody
    • Cadherin 11 antibody
    • Cadherin 11 type 2 antibody
    • Cadherin 11 type 2 OB cadherin (osteoblast) antibody
    • Cadherin-11 antibody
    • Cdh11 antibody
    • CDHOB antibody
    • OB antibody
    • OB-cadherin antibody
    • OBcadherin antibody
    • OSF-4 antibody
    • OSF4 antibody
    • Osteoblast cadherin antibody
    see all

Images

  • Anti-OB Cadherin antibody [16G5] (ab151446) at 1/100 dilution + Scc-1 cells expressing exogenous OB Cadherin

    Predicted band size: 87 kDa

References

This product has been referenced in:

  • Ma C  et al. Combined overexpression of cadherin 6, cadherin 11 and cluster of differentiation 44 is associated with lymph node metastasis and poor prognosis in oral squamous cell carcinoma. Oncol Lett 15:9498-9506 (2018). Read more (PubMed: 29805672) »
  • Kim C  et al. Universal antibody conjugation to nanoparticles using the Fc? receptor I (Fc?RI): quantitative profiling of membrane biomarkers. Bioconjug Chem 25:1893-901 (2014). Read more (PubMed: 25215471) »
See all 2 Publications for this product

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