Overview

  • Product name

  • Description

    Rabbit polyclonal to OB Cadherin
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, ELISAmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    Synthetic peptide corresponding to an internal region of Human OB Cadherin.

  • Positive control

    • Jurkat cell extract.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • Storage buffer

    pH: 7.40
    Preservative: 0.02% Sodium azide
    Constituents: 49% PBS, 50% Glycerol, 0.88% Sodium chloride
    Note: PBS is without Mg2+ and Ca2+
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Purification notes

    ab129760 was affinity-purified from Rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab129760 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 88 kDa.
ELISA 1/20000.

Target

  • Function

    Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
  • Tissue specificity

    Expressed mainly in brain but also found in other tissues. Expressed in neuroblasts.
  • Involvement in disease

    Note=A chromosomal aberration involving CDH11 is a common genetic feature of aneurysmal bone cyst, a benign osseous neoplasm. Translocation t(16;17)(q22;p13) with USP6. The translocation generates a fusion gene in which the strong CDH11 promoter is fused to the entire USP6 coding sequence, resulting in USP6 transcriptional up-regulation.
  • Sequence similarities

    Contains 5 cadherin domains.
  • Cellular localization

    Cell membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • CAD11 antibody
    • CAD11_HUMAN antibody
    • Cadherin 11 antibody
    • Cadherin 11 type 2 antibody
    • Cadherin 11 type 2 OB cadherin (osteoblast) antibody
    • Cadherin-11 antibody
    • Cdh11 antibody
    • CDHOB antibody
    • OB antibody
    • OB-cadherin antibody
    • OBcadherin antibody
    • OSF-4 antibody
    • OSF4 antibody
    • Osteoblast cadherin antibody
    see all

Images

  • All lanes : Anti-OB Cadherin antibody (ab129760) at 1/500 dilution

    Lane 1 : Jurkat cell extract
    Lane 2 : Jurkat cell extract with synthesized peptide

    Predicted band size: 88 kDa

References

ab129760 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab129760.
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