Anti-Obestatin antibody (ab41704)

Reviews (1)Q&A (2)

Key features and details

  • Rabbit polyclonal to Obestatin
  • Reacts with: Mouse, Rat
  • Isotype: IgG

Overview

  • Product name

    Anti-Obestatin antibody
    See all Obestatin primary antibodies

  • Description

    Rabbit polyclonal to Obestatin

  • Host species

    Rabbit

  • Species reactivity

    Reacts with: Mouse, Rat
    Predicted to work with: Cat, Dog, Human, Macaque monkey, Gerbil

  • Immunogen

    Synthetic peptide corresponding to Rat Obestatin aa 1-23.
    Sequence:

    FNAPFDVGIKLSGAQYQQHGRAL


    (Peptide available as ab41821)
    Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI

  • General notes

    Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.

    Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.

    We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.

    In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.

    We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.

    Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.

    Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.

Properties

Target

  • Relevance

    Obestatin, is generated from the proteolytic cleavage of preproghrelin; its sequence corresponds to aamino acids 76-98 of Appetite-regulating hormone [Precursor](Q9QYH7). This peptide has contrasting actions to Ghrelin (a different product of proteolytic cleavage of preproghrelin) in that it inhibits food intake and gastrointestinal motility but does not modify in vitro GH release from pituitary cells.

  • Cellular localization

    Secreted

  • Database links

    • Alternative names

      • Appetite-regulating hormone antibody
      • Growth hormone secretagogue antibody
      • Growth hormone-releasing peptide antibody
      • Motilin-related peptide antibody
      • obestatin 13 antibody
      • Obestatin 23 antibody
      • obestatin-13 antibody
      • Obestatin-23 antibody
      • obestatin13 antibody
      • Obestatin23 antibody
      see all

    References (0)

    Publishing research using ab41704? Please let us know so that we can cite the reference in this datasheet.

    ab41704 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

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    1-3 of 3 Abreviews or Q&A

    IHC - Wholemount abreview for Anti-Obestatin antibody

     Excellent
    Abreviews
    abreview image
    Application
    IHC - Wholemount
    Sample
    Sheep Tissue (Duodenum)
    Specification
    Duodenum
    Read More

    Michal Szlis

    Verified customer

    Submitted Jan 30 2014

    Question

    What species and tissue samples were used to characterise the anti-Obestatin in Western Blot?

    Read More
    Answer

    Les tissus qui ont été utilisés avec le ab41704 sont : Pour le rat : estomac, cerveau, foie, poumons, muscle et reins. Pour la souris : cerveau, intestin grêle et foie. Les meilleurs résultats ont été obtenus avec le cerveau (souris et rat). J'espère que ces informations vous seront utiles. N'hésitez pas à nous contacter de nouveau si vous avez d'autres questions.

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    Question

    1) What species and tissue samples were used to characterise the anti-Obestatin in Western Blot? 2) Does the anti-Obestatin antibody recognise the precusor?

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    Answer

    Un collaborateur du laboratoire vient de m'informer que le western blot dont il dispose actuellement a été obtenu avec le peptide synthétique uniquement; peptide correspondant à l'obestatine-23 de rat (forme clivée). Cette personne m'a confirmé que cet anticorps a également été testé sur échantillons de souris et de rat. J'ai demandé des détails sur les tissus ayant été testés, je vous enverrai cette information dès que j'en aurai pris connaissance. Puisque cet anticorps reconnait l'obestatine-23 (aa 76-98 de la référence SwissProt/UniProt Q9QYH7), je pense que cet anticorps peut donc également reconnaitre le précurseur long de 117 acides aminés. J'espère que ces informations vous seront utiles. N'hésitez pas à nous contacter de nouveau si vous avez d'autres questions.

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