Overview

  • Product name

  • Description

    Rabbit polyclonal to OBSL1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant full length protein corresponding to Human OBSL1 aa 1-61.
    Database link: Q6P710

  • Positive control

    • WB: HepG2, MCF7 and A549 cell lysate. IHC: Human placenta tissue.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    pH: 7.4
    Preservative: 0.03% Proclin
    Constituents: 50% Glycerol, PBS
  • Concentration information loading...
  • Purity

    Protein G purified
  • Clonality

    Polyclonal
  • Isotype

    IgG

Applications

Our Abpromise guarantee covers the use of ab224588 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/5000. Detects a band of approximately 207 kDa (predicted molecular weight: 207 kDa).
IHC-P 1/20 - 1/200.

Target

  • Tissue specificity

    Widely expressed, with predominant levels found in the heart.
  • Involvement in disease

    Defects in OBSL1 are the cause of 3M syndrome type 2 (3M2) [MIM:612921]. An autosomal recessive disorder characterized by severe pre- and postnatal growth retardation, facial dysmorphism, large head circumference, and normal intelligence and endocrine function. Skeletal changes include long slender tubular bones and tall vertebral bodies.
  • Sequence similarities

    Contains 1 fibronectin type-III domain.
    Contains 11 Ig-like (immunoglobulin-like) domains.
  • Information by UniProt
  • Database links

  • Alternative names

    • KIAA0657 antibody
    • Obscurin-like protein 1 antibody
    • OBSL1 antibody
    • OBSL1_HUMAN antibody

Images

  • All lanes : Anti-OBSL1 antibody (ab224588) at 1/500 dilution

    Lane 1 : HepG2 (human liver hepatocellular carcinoma cell line) cell lysate
    Lane 2 : MCF7 (human breast adenocarcinoma cell line) cell lysate
    Lane 3 : A549 (human lung carcinoma cell line) cell lysate

    Secondary
    All lanes : Goat polyclonal to rabbit IgG at 1/50000 dilution

    Predicted band size: 207 kDa
    Observed band size: 207 kDa

  • Paraffin-embedded human placenta tissue stained for OBSL1 using ab224588 at 1/100 dilution in immunohistochemical analysis.

References

ab224588 has not yet been referenced specifically in any publications.

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