Overview

  • Product name
    Anti-Oct-1 antibody, prediluted
    See all Oct-1 primary antibodies
  • Description
    Rabbit polyclonal to Oct-1, prediluted
  • Host species
    Rabbit
  • Tested applications
    Suitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    corresponding to Human Oct-1 (C terminal).
    Database link: P14859

  • Positive control
    • Tonsil

Properties

  • Form
    Prediluted
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C. Avoid freeze / thaw cycle.
  • Storage buffer
    pH: 7.60
    Preservative: 0.1% Sodium azide
    Constituents: 0.605% Tris, 98% BSA
  • Concentration information loading...
  • Purity
    Protein A purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab15113 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P
  • Application notes
    IHC-P: Use at an assay dependent dilution. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. Modulates transcription transactivation by NR3C1, AR and PGR (By similarity). In case of human herpes simplex virus (HSV) infection, POU2F1 forms a multiprotein-DNA complex with the viral transactivator protein VP16 and HCFC1 thereby enabling the transcription of the viral immediate early genes.
    • Tissue specificity
      Ubiquitous. Isoform 2 is lymphocyte-specific.
    • Sequence similarities
      Belongs to the POU transcription factor family. Class-2 subfamily.
      Contains 1 homeobox DNA-binding domain.
      Contains 1 POU-specific domain.
    • Post-translational
      modifications
      Phosphorylated by PRKDC.
    • Cellular localization
      Nucleus.
    • Information by UniProt
    • Database links
    • Alternative names
      • FLJ42836 antibody
      • NF A1 antibody
      • NF-A1 antibody
      • Oct 1 antibody
      • Oct 1B antibody
      • Oct-1 antibody
      • OCT1 antibody
      • Octamer binding protein 1 antibody
      • Octamer binding transcription factor 1 antibody
      • Octamer-binding protein 1 antibody
      • Octamer-binding transcription factor 1 antibody
      • OTF 1 antibody
      • OTF-1 antibody
      • OTF1 antibody
      • OTTHUMP00000032348 antibody
      • OTTHUMP00000032350 antibody
      • OTTHUMP00000032351 antibody
      • PO21 antibody
      • PO2F1 antibody
      • PO2F1_HUMAN antibody
      • POU class 2 homeobox 1 antibody
      • POU domain class 2 transcription factor 1 antibody
      • POU domain, class 2, transcription factor 1 antibody
      • POU2F1 antibody
      see all

    Images

    • ab15113 staining Oct-1 in human tonsil by Immunohistochemistry (Formalin/ PFA fixed paraffin embedded tissue sections).

    References

    ab15113 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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