Overview

  • Product name

  • Description

    Rabbit polyclonal to ODZ3
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide corresponding to Human ODZ3 (internal sequence). (NP_001073946).
    Database link: Q9P273

  • Positive control

    • Human lung cancer and ovarian cancer tissues.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    pH: 7.3
    Preservative: 0.05% Sodium azide
    Constituents: 49% PBS, 50% Glycerol
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab198923 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/100 - 1/300.

Target

  • Function

    Involved in neural development, regulating the establishment of proper connectivity within the nervous system. Promotes axon guidance and homophilic cell adhesion. Plays a role in the development of the visual pathway; regulates the formation in ipsilateral retinal mapping to both the dorsal lateral geniculate nucleus (dLGN) and the superior colliculus (SC). May be involved in the differentiation of the fibroblast-like cells in the superficial layer of mandibular condylar cartilage into chondrocytes. May function as a cellular signal transducer.
  • Tissue specificity

    Expressed in adult and fetal brain, slightly lower levels in testis and ovary, and intermediate levels in all other peripheral tissues examined. Not expressed in spleen or liver. Expression was high in brain, with highest levels in amygdala and caudate nucleus, followed by thalamus and subthalamic nucleus.
  • Involvement in disease

    Microphthalmia, isolated, with coloboma, 9
  • Sequence similarities

    Belongs to the tenascin family. Teneurin subfamily.
    Contains 8 EGF-like domains.
    Contains 5 NHL repeats.
    Contains 1 teneurin N-terminal domain.
    Contains 23 YD repeats.
  • Domain

    EGF-like domains 2 and 5 which have an odd number of cysteines might enable the formation of intermolecular disulfide bonds.
    Cytoplasmic proline-rich regions could serve as docking domains for intracellular SH3-containing proteins.
  • Cellular localization

    Membrane. Cell projection, axon.
  • Information by UniProt
  • Database links

  • Alternative names

    • FLJ10474 antibody
    • FLJ10886 antibody
    • KIAA1455 antibody
    • odd Oz Ten m homolog 3 antibody
    • odz odd Oz ten m homolog 3 (Drosophila) antibody
    • odz odd Oz ten m homolog 3 antibody
    • ODZ3 like protein antibody
    • Protein Odd Oz ten m homolog 3 antibody
    • Protein Odd Oz/ten-m homolog 3 antibody
    • Ten 3 antibody
    • Ten M3 antibody
    • Ten-3 antibody
    • Ten-m3 antibody
    • TEN3_HUMAN antibody
    • Tenascin M3 antibody
    • Tenascin-M3 antibody
    • Teneurin 3 antibody
    • Teneurin transmembrane protein 3 antibody
    • Teneurin-3 antibody
    • Teneurin3 antibody
    • tenm3 antibody
    • TNM3 antibody
    see all

Images

  • Immunohistochemical analysis of paraffin-embedded Human ovarian cancer tissue labeling ODZ3 with ab198923 at 1/50 dilution.

  • Immunohistochemical analysis of paraffin-embedded Human lung cancer tissue labeling ODZ3 with ab198923 at 1/50 dilution.

References

This product has been referenced in:

  • Hartmann H  et al. Proteomics and C9orf72 neuropathology identify ribosomes as poly-GR/PR interactors driving toxicity. Life Sci Alliance 1:e201800070 (2018). Read more (PubMed: 30456350) »
See 1 Publication for this product

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