Key features and details
- Rabbit polyclonal to ODZ3
- Suitable for: IHC-P
- Reacts with: Mouse, Human
- Isotype: IgG
Product nameAnti-ODZ3 antibody
See all ODZ3 primary antibodies
DescriptionRabbit polyclonal to ODZ3
Tested applicationsSuitable for: IHC-Pmore details
Species reactivityReacts with: Mouse, Human
Synthetic peptide corresponding to Human ODZ3 (internal sequence). (NP_001073946).
Database link: Q9P273
- Human lung cancer and ovarian cancer tissues.
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.4
Preservative: 0.05% Sodium azide
Constituents: 49% PBS, 50% Glycerol (glycerin, glycerine)
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab198923 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||1/100 - 1/300.|
FunctionInvolved in neural development, regulating the establishment of proper connectivity within the nervous system. Promotes axon guidance and homophilic cell adhesion. Plays a role in the development of the visual pathway; regulates the formation in ipsilateral retinal mapping to both the dorsal lateral geniculate nucleus (dLGN) and the superior colliculus (SC). May be involved in the differentiation of the fibroblast-like cells in the superficial layer of mandibular condylar cartilage into chondrocytes. May function as a cellular signal transducer.
Tissue specificityExpressed in adult and fetal brain, slightly lower levels in testis and ovary, and intermediate levels in all other peripheral tissues examined. Not expressed in spleen or liver. Expression was high in brain, with highest levels in amygdala and caudate nucleus, followed by thalamus and subthalamic nucleus.
Involvement in diseaseMicrophthalmia, isolated, with coloboma, 9
Sequence similaritiesBelongs to the tenascin family. Teneurin subfamily.
Contains 8 EGF-like domains.
Contains 5 NHL repeats.
Contains 1 teneurin N-terminal domain.
Contains 23 YD repeats.
DomainEGF-like domains 2 and 5 which have an odd number of cysteines might enable the formation of intermolecular disulfide bonds.
Cytoplasmic proline-rich regions could serve as docking domains for intracellular SH3-containing proteins.
Cellular localizationMembrane. Cell projection, axon.
- Information by UniProt
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ab198923 has been referenced in 1 publication.
- Hartmann H et al. Proteomics and C9orf72 neuropathology identify ribosomes as poly-GR/PR interactors driving toxicity. Life Sci Alliance 1:e201800070 (2018). PubMed: 30456350