Overview

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer
    pH: 7.30
    Preservative: 0.02% Sodium azide
    Constituents: Tris buffered saline, 0.5% BSA
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Purification notes
    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Fast track antibodies constitute a diverse group of products that have been released to accelerate your research, but are not yet fully characterized. They have all been affinity purified and show high titre values against the immunizing peptide (by ELISA). Fast track terms of use

Application Abreviews Notes
WB Use at an assay dependent concentration. Predicted molecular weight: 73 kDa.

Preliminary experiments in Human brain, kidney, liver and lung lysates gave no specific signal but low background (at antibody concentration up to 1 µg/ml). 

ELISA Use at an assay dependent concentration.

This antibody gave a positive result in ELISA against the immunizing peptide. Antibody detection limit dilution 1:4,000.

Target

  • Function
    Receptor for opioid growth factor (OGF), also known as Met-enkephalin. Seems to be involved in growth regulation.
  • Tissue specificity
    Highly expressed in the heart and liver, moderately in skeletal muscle and kidney and to a lesser extent in brain and pancreas. Expressed in fetal tissues including liver and kidney.
  • Sequence similarities
    Belongs to the opioid growth factor receptor family.
  • Post-translational
    modifications
    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Cellular localization
    Cytoplasm. Nucleus. The OGF/OGFR complex is probably translocated to the nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • 7 60 protein antibody
    • HGNC:15768 antibody
    • Met enkephalin receptor antibody
    • OGFr antibody
    • OGFR_HUMAN antibody
    • Opioid growth factor receptor antibody
    • Protein 7-60 antibody
    • Zeta Opioid Receptor antibody
    • Zeta type opioid receptor antibody
    • Zeta-type opioid receptor antibody
    see all

References

ab42493 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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