Overview

  • Product name

  • Description

    Rabbit polyclonal to OGR1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat, Horse
  • Immunogen

    Synthetic peptide corresponding to a region within internal amino acids 153-202 (SIYFLMHEEV IEDENQHRVC FEHYPIQAWQ RAINYYRFLV GFLFPICLLL) of Human GPR68 (NP_003476).

  • Positive control

    • Human fetal brain lysate

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer

    Preservative: 0.09% Sodium azide
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab133818 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 41 kDa.Can be blocked with OGR1 peptide (ab182181).

Target

  • Function

    Proton-sensing receptor involved in pH homeostasis. May represents an osteoblastic pH sensor regulating cell-mediated responses to acidosis in bone. Mediates its action by association with G proteins that stimulates inositol phosphate (IP) production or Ca(2+) mobilization. The receptor is almost silent at pH 7.8 but fully activated at pH 6.8. Function also as a metastasis suppressor gene in prostate cancer.
  • Tissue specificity

    Found at low level in a wide range of tissues, but significantly expressed in lung, kidney, bone and nervous system.
  • Sequence similarities

    Belongs to the G-protein coupled receptor 1 family.
  • Cellular localization

    Cell membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • G protein coupled receptor 68 antibody
    • G-protein coupled receptor 68 antibody
    • GPR 12A antibody
    • GPR 68 antibody
    • GPR12A antibody
    • Gpr68 antibody
    • MGC111379 antibody
    • MGC156983 antibody
    • OGR 1 antibody
    • OGR-1 antibody
    • OGR1 antibody
    • OGR1_HUMAN antibody
    • Ovarian cancer G protein coupled receptor 1 antibody
    • Ovarian cancer G-protein coupled receptor 1 antibody
    • Sphingosylphosphorylcholine receptor antibody
    see all

Images

  • Anti-OGR1 antibody (ab133818) at 1 µg/ml + Human fetal brain lysate at 10 µg

    Predicted band size: 41 kDa

References

ab133818 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab133818.
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