Key features and details
- Rabbit polyclonal to OGR1
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Product nameAnti-OGR1 antibody
See all OGR1 primary antibodies
DescriptionRabbit polyclonal to OGR1
Tested applicationsSuitable for: IHC-Pmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse
Synthetic peptide corresponding to Human OGR1 (N terminal) conjugated to Keyhole Limpet Haemocyanin (KLH).
- Human Testis.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferpH: 7.70
Preservative: 0.1% Sodium azide
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab61420 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||Use a concentration of 20 µg/ml.|
FunctionProton-sensing receptor involved in pH homeostasis. May represents an osteoblastic pH sensor regulating cell-mediated responses to acidosis in bone. Mediates its action by association with G proteins that stimulates inositol phosphate (IP) production or Ca(2+) mobilization. The receptor is almost silent at pH 7.8 but fully activated at pH 6.8. Function also as a metastasis suppressor gene in prostate cancer.
Tissue specificityFound at low level in a wide range of tissues, but significantly expressed in lung, kidney, bone and nervous system.
Sequence similaritiesBelongs to the G-protein coupled receptor 1 family.
Cellular localizationCell membrane.
- Information by UniProt
- G protein coupled receptor 68 antibody
- G-protein coupled receptor 68 antibody
- GPR 12A antibody
ab61420 has been referenced in 1 publication.
- Wiley SZ et al. GPR68, a proton-sensing GPCR, mediates interaction of cancer-associated fibroblasts and cancer cells. FASEB J 32:1170-1183 (2018). PubMed: 29092903