Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR12712] to OGT / O-Linked N-Acetylglucosamine Transferase
- Suitable for: WB
- Reacts with: Mouse, Rat, Human
Product nameAnti-OGT / O-Linked N-Acetylglucosamine Transferase antibody [EPR12712]
See all OGT / O-Linked N-Acetylglucosamine Transferase primary antibodies
DescriptionRabbit monoclonal [EPR12712] to OGT / O-Linked N-Acetylglucosamine Transferase
Tested applicationsSuitable for: WBmore details
Unsuitable for: Flow Cyt,ICC/IF,IHC-P or IP
Species reactivityReacts with: Mouse, Rat, Human
Synthetic peptide within Human OGT/ O-Linked N-Acetylglucosamine Transferase aa 100-200 (Cysteine residue). The exact sequence is proprietary.
Database link: O15294
- A549, U87-MG, HeLa, and 293T cell lysates
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 9% PBS, 40% Glycerol, 0.05% BSA, 50% Tissue culture supernatant
Concentration information loading...
PurityTissue culture supernatant
Our Abpromise guarantee covers the use of ab181361 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/1000 - 1/5000. Predicted molecular weight: 116 kDa.|
FunctionAddition of nucleotide-activated sugars directly onto the polypeptide through O-glycosidic linkage with the hydroxyl of serine or threonine. Mediates the O-glycosylation of MLL5 and HCFC1. Promotes proteolytic maturation of HCFC1.
Tissue specificityHighly expressed in pancreas and to a lesser extent in skeletal muscle, heart, brain and placenta. Present in trace amounts in lung and liver.
PathwayProtein modification; protein glycosylation.
Sequence similaritiesBelongs to the O-GlcNAc transferase family.
Contains 13 TPR repeats.
DomainThe TPR repeat domain mediates recognition of protein substrates.
modificationsUbiquitinated, leading to its proteasomal degradation.
Cellular localizationCytoplasm. Nucleus. Mostly in the nucleus.
- Information by UniProt
- FLJ23071 antibody
- GlcNAc transferase antibody
- HRNT1 antibody
ab181361 has not yet been referenced specifically in any publications.