• Product name

    Anti-Olig1 antibody [EPR6790]
    See all Olig1 primary antibodies
  • Description

    Rabbit monoclonal [EPR6790] to Olig1
  • Host species

  • Tested applications

    Suitable for: WB, Flow Cytmore details
    Unsuitable for: ICC,IHC-P or IP
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide (the amino acid sequence is considered to be commercially sensitive)

  • Positive control

    • MOLT4, SHSY-5Y, 293T and C6 cell lysates; 293T cells
  • General notes



    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.



Our Abpromise guarantee covers the use of ab124908 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Detects a band of approximately 35 kDa (predicted molecular weight: 27 kDa).
Flow Cyt 1/10 - 1/100.

ab172730 - Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.


  • Application notes
    Is unsuitable for ICC,IHC-P or IP.
  • Target

    • Function

      Promotes formation and maturation of oligodendrocytes, especially within the brain. Cooperates with OLIG2 to establish the pMN domain of the embryonic neural tube.
    • Tissue specificity

      Expressed in the brain, in oligodendrocytes. Strongly expressed in oligodendrogliomas, while expression is weak to moderate in astrocytomas. Expression in glioblastomas is highly variable.
    • Sequence similarities

      Contains 1 basic helix-loop-helix (bHLH) domain.
    • Cellular localization

    • Information by UniProt
    • Database links

    • Alternative names

      • Basic domain helix loop helix protein class B 6 antibody
      • Basic domain helix loop helix protein class B6 antibody
      • BHLH B6 antibody
      • BHLHB 6 antibody
      • bHLHb6 antibody
      • bHLHe21 antibody
      • Class B basic helix-loop-helix protein 6 antibody
      • Class E basic helix-loop-helix protein 21 antibody
      • Olig 1 antibody
      • Olig1 antibody
      • OLIG1_HUMAN antibody
      • Oligo 1 antibody
      • Oligo1 antibody
      • Oligodendrocyte lineage transcription factor 1 antibody
      • Oligodendrocyte specific bHLH transcription factor 1 antibody
      • Oligodendrocyte transcription factor 1 antibody
      see all


    • All lanes : Anti-Olig1 antibody [EPR6790] (ab124908) at 1/1000 dilution

      Lane 1 : MOLT4 cell lysate
      Lane 2 : SHSY-5Y cell lysate
      Lane 3 : 293T cell lysate
      Lane 4 : C6 cell lysate

      Lysates/proteins at 10 µg per lane.

      All lanes : HRP labelled goat anti-rabbit at 1/2000 dilution

      Predicted band size: 27 kDa
      Observed band size: 35 kDa
      why is the actual band size different from the predicted?

    • Flow cytometric analysis of permeabilized 293T cells using ab124908 at 1/10 dilution (red) or a rabbit IgG negative control (green).
    • Equilibrium disassociation constant (KD)
      Learn more about KD

      Click here to learn more about KD


    This product has been referenced in:

    • Cheng T  et al. Effect of OLIG1 on the development of oligodendrocytes and myelination in a neonatal rat PVL model induced by hypoxia-ischemia. Mol Med Rep 11:2379-86 (2015). WB, IHC ; Rat . Read more (PubMed: 25435330) »
    See 1 Publication for this product

    Customer reviews and Q&As


    Not sure exactly why Olig1 runs a bit slower than would be suggested based on theoretical mass alone. It doesn't appear to be post translationally modified. But another Olig1 antibody in our catalog, ab97507 https://www.abcam.com/Olig1-antibody-ab97507.html) also runs at the same molecular mass.

    Read More

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