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Neuroscience Cell Type Marker Glia marker Oligodendrocyte marker
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RecombinantRabMAb

Recombinant Anti-Oligodendrocyte Specific Protein antibody [EPR12726] (ab175236)

  • Datasheet
  • SDS
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Western blot - Anti-Oligodendrocyte Specific Protein antibody [EPR12726] (ab175236)
  • Flow Cytometry - Anti-Oligodendrocyte Specific Protein antibody [EPR12726] (ab175236)
  • Anti-Oligodendrocyte Specific Protein antibody [EPR12726] (ab175236)

Key features and details

  • Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
  • Rabbit monoclonal [EPR12726] to Oligodendrocyte Specific Protein
  • Suitable for: WB, Flow Cyt
  • Reacts with: Human

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Overview

  • Product name

    Anti-Oligodendrocyte Specific Protein antibody [EPR12726]
    See all Oligodendrocyte Specific Protein primary antibodies
  • Description

    Rabbit monoclonal [EPR12726] to Oligodendrocyte Specific Protein
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, Flow Cytmore details
    Unsuitable for: ICC/IF,IHC-P or IP
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat, Cow, Cynomolgus monkey, Orangutan
  • Immunogen

    Synthetic peptide within Human Oligodendrocyte Specific Protein aa 1-100 (Cysteine residue). The exact sequence is proprietary.
    Database link: O75508

  • Positive control

    • Human oligodendroglioma, U87-MG, SH-SY5Y, fetal brain and Human testis lysates; U87-MG cells.
  • General notes

    This product is a recombinant monoclonal antibody, which offers several advantages including:

    • - High batch-to-batch consistency and reproducibility
    • - Improved sensitivity and specificity
    • - Long-term security of supply
    • - Animal-free production
    For more information see here.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    pH: 7.20
    Preservative: 0.01% Sodium azide
    Constituents: 9% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA, 50% Tissue culture supernatant
  • Concentration information loading...
  • Purity

    Tissue culture supernatant
  • Clonality

    Monoclonal
  • Clone number

    EPR12726
  • Isotype

    IgG
  • Research areas

    • Neuroscience
    • Cell Type Marker
    • Glia marker
    • Oligodendrocyte marker
    • Immunology
    • Immune System Diseases
    • Autoimmune
    • Neuroscience
    • Neurology process
    • Neurodegenerative disease
    • Other

Associated products

  • Alternative Versions

    • Anti-Oligodendrocyte Specific Protein antibody [EPR12726] - BSA and Azide free (ab249885)
  • Isotype control

    • Rabbit IgG, monoclonal [EPR25A] - Isotype Control (ab172730)
  • Recombinant Protein

    • Recombinant Human Oligodendrocyte Specific Protein (ab131748)
  • Related Products

    • Recombinant Human Oligodendrocyte Specific Protein (ab131748)

Applications

The Abpromise guarantee

Our Abpromise guarantee covers the use of ab175236 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
1/1000 - 1/10000. Predicted molecular weight: 22 kDa.
Flow Cyt
1/100 - 1/500.

ab172730 - Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.

 

Notes
WB
1/1000 - 1/10000. Predicted molecular weight: 22 kDa.
Flow Cyt
1/100 - 1/500.

ab172730 - Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.

 

  • Application notes
    Is unsuitable for ICC/IF,IHC-P or IP.
  • Target

    • Function

      Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
    • Sequence similarities

      Belongs to the claudin family.
    • Cellular localization

      Cell junction > tight junction. Cell membrane.
    • Target information above from: UniProt accession O75508 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt
    • Database links

      • Entrez Gene: 508268. Cow
      • Entrez Gene: 5010 Human
      • Entrez Gene: 18417 Mouse
      • Entrez Gene: 84588 Rat
      • Omim: 601326 Human
      • SwissProt: Q3MHK4 Cow
      • SwissProt: Q4R3L1 Cynomolgus monkey
      • SwissProt: O75508 Human
      • SwissProt: Q60771 Mouse
      • SwissProt: Q5REK8 Orangutan
      • SwissProt: Q99P82 Rat
      • Unigene: 31595 Human
      • Unigene: 4425 Mouse
      • Unigene: 8282 Rat
      see all
    • Alternative names

      • Claudin 11 antibody
      • Claudin-11 antibody
      • CLD11_HUMAN antibody
      • Cldn11 antibody
      • Oligodendrocyte transmembrane protein antibody
      • Oligodendrocyte-specific protein antibody
      • OSP antibody
      • OTM antibody
      see all

    Images

    • Western blot - Anti-Oligodendrocyte Specific Protein antibody [EPR12726] (ab175236)
      Western blot - Anti-Oligodendrocyte Specific Protein antibody [EPR12726] (ab175236)
      All lanes : Anti-Oligodendrocyte Specific Protein antibody [EPR12726] (ab175236) at 1/1000 dilution

      Lane 1 : Human oligodendroglioma lysate
      Lane 2 : U87-MG lysate
      Lane 3 : SH-SY5Y lysate
      Lane 4 : Fetal brain lysate
      Lane 5 : Human testis lysate

      Lysates/proteins at 10 µg per lane.

      Predicted band size: 22 kDa

    • Flow Cytometry - Anti-Oligodendrocyte Specific Protein antibody [EPR12726] (ab175236)
      Flow Cytometry - Anti-Oligodendrocyte Specific Protein antibody [EPR12726] (ab175236)

      Flow Cytometrical analysis of  U87-MG cells labeling Oligodendrocyte Specific Protein with ab175236 antibody at a dilution of 1/100 (red) or a rabbit IgG (negative) (green).

    • Anti-Oligodendrocyte Specific Protein antibody [EPR12726] (ab175236)
      Anti-Oligodendrocyte Specific Protein antibody [EPR12726] (ab175236)

    Protocols

    • Western blot protocols
    • Flow cytometry protocols

    Click here to view the general protocols

    Datasheets and documents

    • SDS download

    • Datasheet download

      Download

    References (2)

    Publishing research using ab175236? Please let us know so that we can cite the reference in this datasheet.

    ab175236 has been referenced in 2 publications.

    • Wang J  et al. Androgen promotes differentiation of PLZF+ spermatogonia pool via indirect regulatory pattern. Cell Commun Signal 17:57 (2019). PubMed: 31142324
    • Wang B  et al. Oridonin overcomes the gemcitabine resistant PANC-1/Gem cells by regulating GST pi and LRP/1 ERK/JNK signalling. Onco Targets Ther 12:5751-5765 (2019). PubMed: 31410021

    Customer reviews and Q&As

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