Overview

  • Product name

    Olsalazine sodium, Anti-inflammatory agent
  • Description

    Anti-inflammatory agent
  • Biological description

    Anti-inflammatory agent. Prodrug of Mesalamine (Asc 3052). Shows anticolitis effects in vivo. Orally active.
  • Purity

    > 98%
  • CAS Number

    6054-98-4
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    5-[(E)-2-(3-Carboxy-4-hydroxyphenyl)diazen-1-yl]-2-hydroxybenzoic acid disodium salt
  • Molecular weight

    346.20
  • Molecular formula

    C14H8N2Na2O6
  • PubChem identifier

    54727588
  • Storage instructions

    Store at Room Temperature. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in water to 100 mM and in DMSO to 10 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    Oc1ccc(cc1C(=O)O[Na])/N=N/c2cc(C(=O)O[Na])c(O)cc2
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Sann H  et al. Efficacy of drugs used in the treatment of IBD and combinations thereof in acute DSS-induced colitis in mice. Life Sci 92:708-18 (2013). Read more (PubMed: 23399699) »
  • Chawla A  et al. Effect of olsalazine on sodium-dependent bile acid transport in rat ileum. Dig Dis Sci 40:943-8 (1995). Read more (PubMed: 7729283) »
  • Odlind B & Eriksson O Olsalazine sodium stimulates chloride transport across the bullfrog cornea. Acta Physiol Scand 139:241-2 (1990). Read more (PubMed: 2356752) »

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