Overview

  • Product name

    Ondansetron hydrochloride, 5-HT3 receptor antagonist
  • Description

    Potent, selective 5-HT3 receptor antagonist
  • Biological description

    Potent, selective 5-HT3 receptor antagonist (Ki = 6.16 nM). Potent antiemetic in vivo.
  • Purity

    > 99%
  • CAS Number

    99614-01-4
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Ginawi OT  et al. Ondansetron, a selective 5-HT3 antagonist, antagonizes methamphetamine-induced anorexia in mice. Pharmacol Res 51:255-9 (2005). Read more (PubMed: 15661576) »
  • Ye JH  et al. Ondansetron: a selective 5-HT(3) receptor antagonist and its applications in CNS-related disorders. CNS Drug Rev 7:199-213 (2001). Read more (PubMed: 11474424) »
  • Youssefyeh RD  et al. Development of high-affinity 5-HT3 receptor antagonists. 1. Initial structure-activity relationship of novel benzamides. J Med Chem 35:895-903 (1992). Read more (PubMed: 1312602) »

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