Overview

  • Product name

    ONO-RS-082, phospholipase A2 (PLA2) inhibitor
  • Description

    Potent, reversible phospholipase A2 (PLA2) inhibitor
  • Biological description

    Potent, reversible PLA2 inhibitor (IC50 = 7 µM). Cell-permeable. Active in ex vivo preparations.
  • Purity

    > 98%
  • CAS Number

    99754-06-0
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Macianskiene R  et al. Induction of a novel cation current in cardiac ventricular myocytes by flufenamic acid and related drugs. Br J Pharmacol 161:416-29 (2010). Read more (PubMed: 20735425) »
  • Schmidt JA  et al. A role for phospholipase A2 activity in membrane tubule formation and TGN trafficking. Traffic 11:1530-6 (2010). Read more (PubMed: 20874826) »
  • Kurosawa M  et al. Effect of phospholipase A2 inhibitor ONO-RS-082 on substance P-induced histamine release from rat peritoneal mast cells. Int Arch Allergy Immunol 97:226-8 (1992). Read more (PubMed: 1375204) »

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