Anti-OPRT antibody (ab234676)
Key features and details
- Rabbit polyclonal to OPRT
- Suitable for: WB
- Reacts with: Recombinant fragment
- Isotype: IgG
Overview
-
Product name
Anti-OPRT antibody
See all OPRT primary antibodies -
Description
Rabbit polyclonal to OPRT -
Host species
Rabbit -
Specificity
Predicted to react with Laribacter hongkongensis. -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Recombinant fragment -
Immunogen
Recombinant full length protein corresponding to OPRT aa 1 to the C-terminus. (Laribacter hongkongensis)
Database link: C1D6F5 -
Positive control
- WB: Recombinant Laribacter hongkongensis OPRT protein.
-
General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
-
Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.40
Preservative: 0.03% Proclin 300
Constituents: PBS, 50% Glycerol (glycerin, glycerine) -
Concentration information loading...
-
Purity
Protein G purified -
Purification notes
Purity >95%. -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
-
Compatible Secondaries
-
Isotype control
-
Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab234676 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
WB |
1/500 - 1/5000. Detects a band of approximately 23 kDa (predicted molecular weight: 23 kDa).
|
Notes |
---|
WB
1/500 - 1/5000. Detects a band of approximately 23 kDa (predicted molecular weight: 23 kDa). |
Target
-
Pathway
Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from orotate: step 1/2.
Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from orotate: step 2/2. -
Involvement in disease
Defects in UMPS are the cause of orotic aciduria type 1 (ORAC1) [MIM:258900]. A disorder of pyrimidine metabolism resulting in megaloblastic anemia and orotic acid crystalluria that is frequently associated with some degree of physical and mental retardation. A minority of cases have additional features, particularly congenital malformations and immune deficiencies. -
Sequence similarities
In the N-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
In the C-terminal section; belongs to the OMP decarboxylase family. - Information by UniProt
-
Alternative names
- ODC antibody
- OMPdecase antibody
- OPRT antibody
see all
Images
-
All lanes : Anti-OPRT antibody (ab234676) at 1/500 dilution
Lane 1 : Recombinant Laribacter hongkongensis OPRT protein, 80 ng
Lane 2 : Recombinant Laribacter hongkongensis OPRT protein, 40 ng
Lane 3 : Recombinant Laribacter hongkongensis OPRT protein, 20 ng
Secondary
All lanes : Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 23 kDa
Observed band size: 23 kDa
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
-
SDS download
-
Datasheet download
References (0)
ab234676 has not yet been referenced specifically in any publications.