Product nameAnti-OPRT antibody
See all OPRT primary antibodies
DescriptionRabbit polyclonal to OPRT
SpecificityPredicted to react with Laribacter hongkongensis.
Tested applicationsSuitable for: WBmore details
Recombinant full length protein corresponding to OPRT aa 1-213. (Laribacter hongkongensis)
MSDFRQDFIRFAVEEQVLRFGEFVTKAGRPSPYFFNAGLFNHGASLLSLA RFYARSISESGIAFDMLFGPAYKGIVLAGATAMMLAEQGRDVPFAFNRKE AKDHGEGGTLIGAPLKGRVLIIDDVISAGTSVRESVEIIRANGAEPAGVA IALDRMERGQGELSATQEVAQKFGLPVVAIASLDDLLGFLAGSPDLADNL TRVEAYRTQYGVR
Database link: C1D6F5
- WB: Recombinant Laribacter hongkongensis OPRT protein.
This product was previously labelled as UMPS
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.40
Preservative: 0.03% Proclin
Constituents: PBS, 50% Glycerol
Concentration information loading...
PurityProtein G purified
Purification notesPurity >95%.
Our Abpromise guarantee covers the use of ab234676 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/5000. Detects a band of approximately 23 kDa (predicted molecular weight: 23 kDa).|
PathwayPyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from orotate: step 1/2.
Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from orotate: step 2/2.
Involvement in diseaseDefects in UMPS are the cause of orotic aciduria type 1 (ORAC1) [MIM:258900]. A disorder of pyrimidine metabolism resulting in megaloblastic anemia and orotic acid crystalluria that is frequently associated with some degree of physical and mental retardation. A minority of cases have additional features, particularly congenital malformations and immune deficiencies.
Sequence similaritiesIn the N-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
In the C-terminal section; belongs to the OMP decarboxylase family.
- Information by UniProt
- ODC antibody
- OMPdecase antibody
- OPRT antibody
All lanes : Anti-OPRT antibody (ab234676) at 1/500 dilution
Lane 1 : Recombinant Laribacter hongkongensis OPRT protein, 80 ng
Lane 2 : Recombinant Laribacter hongkongensis OPRT protein, 40 ng
Lane 3 : Recombinant Laribacter hongkongensis OPRT protein, 20 ng
All lanes : Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 23 kDa
Observed band size: 23 kDa
ab234676 has not yet been referenced specifically in any publications.