Overview

  • Product name

    Orbifloxacin, Fluoroquinolone antibiotic
  • Description

    Fluoroquinolone antibiotic
  • Biological description

    Fluoroquinolone antibiotic. Inhibits topoisomerase II ligase resulting in DNA fragmentation.
  • Purity

    > 98%
  • CAS Number

    113617-63-3
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    1-Cyclopropyl-7-[(3S,5R)-3,5-dimethylpiperazin-1-yl]-5,6,8-trifluoro-4-oxoquinoline-3-carboxylic acid
  • Molecular weight

    395.38
  • Molecular formula

    C19H20F3N3O3
  • PubChem identifier

    60605
  • Storage instructions

    Store at Room Temperature. The product can be stored for up to 12 months.
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CC1CN(CC(N1)C)C2=C(C3=C(C(=C2F)F)C(=O)C(=CN3C4CC4)C(=O)O)F
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Harada K  et al. Post-antibiotic effect of orbifloxacin against Escherichia coli and Pseudomonas aeruginosa isolates from dogs. Acta Vet Scand 54:16 (2012). Read more (PubMed: 22433170) »
  • Hawkins MG  et al. Pharmacokinetic-pharmacodynamic integration of orbifloxacin in Japanese quail (Coturnix japonica) following oral and intravenous administration. J Vet Pharmacol Ther 34:350-8 (2011). Read more (PubMed: 20950349) »
  • Tohamy MA Comparative pharmacokinetics of orbifloxacin in healthy and Pasteurella multocida infected ducks. Br Poult Sci 52:639-44 (2011). Read more (PubMed: 22029792) »

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