Key features and details
- Rabbit polyclonal to ORC1
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Product nameAnti-ORC1 antibody
See all ORC1 primary antibodies
DescriptionRabbit polyclonal to ORC1
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Human
Synthetic peptide derived from an internal region of Human ORC1.
- HepG2 cell lysate.
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Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at -20ºC.
Storage bufferpH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 49% PBS, 50% Glycerol (glycerin, glycerine), 0.88% Sodium chloride
PBS is without Mg2+ and Ca2+
Concentration information loading...
PurityImmunogen affinity purified
Purification notesab138102 was affinity-purified from rabbit antiserum by immunogenic peptide affinity-chromatography.
Our Abpromise guarantee covers the use of ab138102 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/1000. Predicted molecular weight: 97 kDa.|
FunctionComponent of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
Sequence similaritiesBelongs to the ORC1 family.
Contains 1 BAH domain.
Developmental stageExpression is cell-cycle regulated, it starts to accumulate in mid-G1 phase, reaches a peak at the G1/S boundary, and decreases to a basal level in S phase (at protein level).
- Information by UniProt
- HSORC1 antibody
- MmORC1 antibody
- orc1 antibody
ab138102 has not yet been referenced specifically in any publications.