Overview

  • Product name

  • Description

    Rabbit polyclonal to ORC1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide derived from an internal region of Human ORC1.

  • Positive control

    • HepG2 cell lysate.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at -20ºC.
  • Storage buffer

    pH: 7.40
    Preservative: 0.02% Sodium azide
    Constituents: 49% PBS, 50% Glycerol, 0.88% Sodium chloride
    Note: PBS is without Mg2+ and Ca2+
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Purification notes

    ab138102 was affinity-purified from rabbit antiserum by immunogenic peptide affinity-chromatography.
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab138102 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 97 kDa.

Target

  • Function

    Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
  • Sequence similarities

    Belongs to the ORC1 family.
    Contains 1 BAH domain.
  • Developmental stage

    Expression is cell-cycle regulated, it starts to accumulate in mid-G1 phase, reaches a peak at the G1/S boundary, and decreases to a basal level in S phase (at protein level).
  • Cellular localization

    Nucleus.
  • Information by UniProt
  • Database links

  • Alternative names

    • HSORC1 antibody
    • MmORC1 antibody
    • orc1 antibody
    • ORC1_HUMAN antibody
    • ORC1L antibody
    • Origin Recognition Complex 1 antibody
    • Origin recognition complex subunit 1 (yeast homolog) like antibody
    • Origin recognition complex subunit 1 antibody
    • Origin recognition complex subunit 1 homolog antibody
    • Origin recognition complex subunit 1 like (S. cerevisia antibody
    • Origin recognition complex subunit 1 like antibody
    • Origin recognition complex subunit 1 S. cerevisiae homolog like antibody
    • Origin recognition complex, subunit 1 like (yeast) antibody
    • PARC1 antibody
    • Replication control protein 1 antibody
    see all

Images

  • Anti-ORC1 antibody (ab138102) at 1/500 dilution + HepG2 cell lysate at 30 µg

    Predicted band size: 97 kDa

References

ab138102 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab138102.
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