Anti-ORC3L antibody - C-terminal (ab153945)
- Datasheet
- References
- Protocols
Overview
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Product name
Anti-ORC3L antibody - C-terminal
See all ORC3L primary antibodies -
Description
Rabbit polyclonal to ORC3L - C-terminal -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Cow, Xenopus laevis, Zebrafish, Xenopus tropicalis
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Immunogen
Synthetic peptide, corresponding to a region within C terminal amino acids 648-711 of Human ORC3L (Uniprot ID Q9UBD5).
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Positive control
- H1299 whole cell lysate; HeLa, HepG2 and A431 cell lines.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: PBS, 40% Glycerol -
Concentration information loading... -
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
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Related Products
Applications
Our Abpromise guarantee covers the use of ab153945 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB | 1/500 - 1/3000. Predicted molecular weight: 82 kDa. |
Target
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Function
Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. -
Sequence similarities
Belongs to the ORC3 family. -
Post-translational
modificationsPhosphorylated upon DNA damage, probably by ATM or ATR.
Phosphorylated upon DNA damage, probably by ATM or ATR. -
Cellular localization
Nucleus. - Information by UniProt
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Database links
- Entrez Gene: 523714 Cow
- Entrez Gene: 23595 Human
- Entrez Gene: 50793 Mouse
- Entrez Gene: 100125181 Xenopus tropicalis
- Entrez Gene: 334315 Zebrafish
- GenBank: NP_862820.1 Human
- Omim: 604972 Human
- SwissProt: Q32PJ3 Cow
see all -
Alternative names
- Homolog of Latheo antibody
- homolog of latheo, Drosophila antibody
- LAT antibody
see all
Images
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Western blot - Anti-ORC3L antibody - C-terminal (ab153945)Anti-ORC3L antibody - C-terminal (ab153945) at 1/1000 dilution + H1299 whole cell lysate at 30 µg
Predicted band size: 82 kDa
7.5% SDS PAGE
Protocols
References
ab153945 has not yet been referenced specifically in any publications.
