Anti-ORC3L antibody - C-terminal (ab153945)
Key features and details
- Rabbit polyclonal to ORC3L - C-terminal
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-ORC3L antibody - C-terminal -
Description
Rabbit polyclonal to ORC3L - C-terminal -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Cow, Xenopus laevis, Zebrafish, Xenopus tropicalis
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Immunogen
Synthetic peptide, corresponding to a region within C terminal amino acids 648-711 of Human ORC3L (Uniprot ID Q9UBD5).
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Positive control
- H1299 whole cell lysate; HeLa, HepG2 and A431 cell lines.
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General notes
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 59.99% PBS, 40% Glycerol (glycerin, glycerine) -
Concentration information loading... -
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
Applications
Our Abpromise guarantee covers the use of ab153945 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB | 1/500 - 1/3000. Predicted molecular weight: 82 kDa. |
Target
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Function
Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. -
Sequence similarities
Belongs to the ORC3 family. -
Post-translational
modificationsPhosphorylated upon DNA damage, probably by ATM or ATR.
Phosphorylated upon DNA damage, probably by ATM or ATR. -
Cellular localization
Nucleus. - Information by UniProt
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Database links
- Entrez Gene: 523714 Cow
- Entrez Gene: 23595 Human
- Entrez Gene: 50793 Mouse
- Entrez Gene: 100125181 Xenopus tropicalis
- Entrez Gene: 334315 Zebrafish
- GenBank: NP_862820.1 Human
- Omim: 604972 Human
- SwissProt: Q32PJ3 Cow
see all -
Alternative names
- Homolog of Latheo antibody
- homolog of latheo, Drosophila antibody
- LAT antibody
see all
Images
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Western blot - Anti-ORC3L antibody - C-terminal (ab153945)Anti-ORC3L antibody - C-terminal (ab153945) at 1/1000 dilution + H1299 whole cell lysate at 30 µg
Predicted band size: 82 kDa
7.5% SDS PAGE
References (0)
ab153945 has not yet been referenced specifically in any publications.
