Key features and details
- Sheep polyclonal to Orexin A
- Suitable for: IHC-Fr, ELISA, IHC-P
- Reacts with: Human
- Isotype: IgG
Product nameAnti-Orexin A antibody
See all Orexin A primary antibodies
DescriptionSheep polyclonal to Orexin A
SpecificityThis antibody reacts with Orexin A.
Tested applicationsSuitable for: IHC-Fr, ELISA, IHC-Pmore details
Species reactivityReacts with: Human
Synthetic Orexin A conjugated to KLH.
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage bufferpH: 7.20
Preservative: 0.09% Sodium azide
Concentration information loading...
PurityAmmonium Sulphate Precipitation
Our Abpromise guarantee covers the use of ab64565 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-Fr||Use at an assay dependent dilution.|
|IHC-P||Use at an assay dependent concentration.|
RelevanceOrexin A (hypocretin 1) a 33 amino acid peptide and orexin B (hypocretin 2), a 28 amino acid peptide, are both derived from a common 130 amino acid precursor, prepro orexin. Orexin A and Orexin B stimulate food consumption when administered intracerebroventricularly to rats. Orexin gene expression in the brain is highly restricted to distinct populations of neurons located in specific hypothalamic regions, including the lateral hypothalamic area (LHA), a region implicated in feeding behaviour. Orexin A and orexin B bind to and activate two closely related G protein coupled receptors (GPCRs), termed Orexin 1 (OX1) and Orexin 2 (OX2) receptors. Dysfunction of the orexin peptide system has been linked to narcolepsy.
Cellular localizationRough endoplasmic reticulum. Cytoplasmic vesicle. Cell junction, synapse. Note: Associated with perikaryal rough endoplasmic reticulum as well as cytoplasmic large granular vesicles at synapses.
- HCRT antibody
- HCRT1 antibody
- HCRT2 antibody
ab64565 has not yet been referenced specifically in any publications.