Key features and details
- Goat polyclonal to Orexin Receptor 1 and 2
- Suitable for: WB
- Reacts with: Mouse, Rat, Human
- Isotype: IgG
Product nameAnti-Orexin Receptor 1 and 2 antibody
DescriptionGoat polyclonal to Orexin Receptor 1 and 2
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Mouse, Rat, Human
Predicted to work with: Chicken, Cow, Dog, Pig, Zebrafish
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferpH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 0.5% BSA, Tris buffered saline
Concentration information loading...
PurityImmunogen affinity purified
Purification notesPurified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Our Abpromise guarantee covers the use of ab77370 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use a concentration of 0.3 - 1 µg/ml. Detects a band of approximately 49 kDa (predicted molecular weight: 49 kDa).
1 hour primary incubation is recommended for this product.
RelevanceOrexins, also called hypocretins, are the common names given to a pair of highly excitatory neuropeptide hormones that were simultaneously discovered by two groups of reseachers in rat brains. The two highly related peptides (orexin A and B, or hypocretin 1 and 2) are produced by cleavage of a single precursor protein. Studies suggest that orexin A/hypocretin 1 may be of greater biological importance than orexin B/hypocretin 2. Although these peptides are produced by a very small population of cells in the lateral and posterior hypothalamus, they send projections throughout the brain. The orexins/hypocretins are strongly conserved peptides, found in all major classes of vertebrates. The peptides are thought to have arisen early in vertebrate evolution.
Cellular localizationMembrane; multi pass membrane protein.
- CD200R antibody
- HCRTR1 antibody
- HCRTR2 antibody
ab77370 has not yet been referenced specifically in any publications.