Anti-Ovine MHC Class II DR antibody [37.68] (ab34007)


  • Product name
    Anti-Ovine MHC Class II DR antibody [37.68]
  • Description
    Mouse monoclonal [37.68] to Ovine MHC Class II DR
  • Host species
  • Tested applications
    Suitable for: Flow Cyt, IP, IHC-Frmore details
  • Species reactivity
    Reacts with: Sheep, Goat, Cow, Human
  • Immunogen

    Splenocytes from ATL mice


  • Form
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer
    Preservative: 0.09% Sodium Azide
    Constituents: PBS, pH 7.4
  • Concentration information loading...
  • Purity
    Protein G purified
  • Purification notes
    Purified from tissue culture supernatant.
  • Clonality
  • Clone number
  • Isotype
  • Research areas


Our Abpromise guarantee covers the use of ab34007 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use 10µl for 106 cells.

Use 1/50 - 1/200, or 10µl of the suggested working dilution to label 106 cells in 100µl.

ab170191 - Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody.


IP Use at an assay dependent concentration.
IHC-Fr Use at an assay dependent concentration.


  • Relevance
    Three subregions of the Major Histocompatibility Complex (MHC), DP, DQ and DR, determine class II molecules, which are essential in the cellular recognition interactions involved in the generation of an immune response. These molecules display processed antigens from virally-infected or transformed cells. Class-II-positive cells (antigen-presenting cells) can take up antigens from outside by endocytosis, degrade them into small peptides, and re-export the peptides (now bound to MHC class II protein) to the cell surface. These peptide-MHC class II complexes can then be recognized by specific CD4+ lymphocytes. Several class II antigens are also associated with disease states. The extremely high polymorphism of MHC class II transmembrane heterodimers is due to a few hypervariable segments present in the most external domain of their alpha and beta chains. The alpha chain of MHC-DR is not polymorphic, whereas the beta chain is highly so. Some changes in amino acid sequence are critical in disease susceptibility associations as well as the ability to present processed antigens to T cells.
  • Cellular localization
    Cell Membrane
  • Alternative names
    • DR alpha chain antibody
    • DR beta 5 antibody
    • HLA class II histocompatibility antigen antibody
    • HLA DRA antibody
    • HLA DRB1 antibody
    • MHC class II antigen DRA antibody
    see all


ab34007 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

1-2 of 2 Abreviews or Q&A


We unfortunately cannot provide ab20147 and ab54217 as FITC conjugated antibodies because we do not custom conjugate the antibodies.

We however have the following anti CD90 FITC conjugated antibodies that may be of your interest

ab226, ab11155, ab25672, ab62009, ab112463, ab112468 and ab124527

We do not have anti CD73 FITC conjugated antibodies in catalogue.

ab11415 is the same FITC conjugated version of ab11414.

Could you choose the antibodies and contact me again.

You will be happy to know that we do have FITC conjugation kits available in catalogue that can be used to conjugate any antibody customer requires. Please check the datasheet of


Please let me know which product you are interested in. I will then send you the discount code.

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Thank you for your email.

CD271: We have ab8877 which is fully tested with Sheep samples and is guaranteed to work.

CD34: ab963, ab8536, ab30375, ab30377 are the sheep specific antibodies.

CD11b: It seems ab75476, ab62817 can cross react due to immunogenic sequence homology.

CD14: No antibodies

CD45: No antibodies

MHC class I: No antibodies

MHC class II: ab34007

Please also find attached the Excel list of target specific antibodies we have. The list may help you in selecting the right antibody.

I hope this info will be helpful. Should you have any other question please do not hesitate to contact me.

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