Oxonic acid potassium salt, Uricase inhibitor (ab146258)

Overview

  • Product name

    Oxonic acid potassium salt, Uricase inhibitor
  • Description

    Uricase inhibitor.
  • Alternative names

    • 4,6-Dihydroxy-1,3,5-triazine-2-carboxylic acid potassium salt
    • Allantoxanic acid
    • Allantoxanic Acid Potassium Salt
    • Oteracil Potassium
    • Potassium Allantoxanate
    • Potassium Azaorotate
    • Potassium Otastat
    • Potassium Oxonate
    see all
  • Biological description

    Uricase inhibitor. Used to induce hyperuricemia in rats as it inhibits uric acid metabolism. Inhibits 5-fluorouracil-induced gastrointestinal toxicity without the loss of its antitumor activity in rats.


     

  • CAS Number

    2207-75-2
  • Chemical structure

    Chemical Structure

Properties

  • Molecular weight

    195.17
  • Molecular formula

    C4H2KN3O4
  • Storage instructions

    Store at Room Temperature. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • Source

    Synthetic

References

This product has been referenced in:

  • Habu Y  et al. Restored expression and activity of organic ion transporters rOAT1, rOAT3 and rOCT2 after hyperuricemia in the rat kidney. Biochem Pharmacol 69:993-9 (2005). Read more (PubMed: 15748710) »
  • Shirasaka T  et al. Inhibition by oxonic acid of gastrointestinal toxicity of 5-fluorouracil without loss of its antitumor activity in rats. Cancer Res 53:4004-9 (1993). Read more (PubMed: 7689420) »

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