Key features and details
- Non-selective muscarinic receptor agonist
- CAS Number: 17360-35-9
- Purity: > 99%
- Soluble in DMSO to 100 mM, in ethanol to 100 mM, in water to 25 mM and in PBS to 25 mM
- Form / State: Solid
- Source: Synthetic
Product nameOxotremorine sesquifumarate, Non-selective muscarinic receptor agonist
DescriptionNon-selective muscarinic receptor agonist
Non-selective muscarinic receptor agonist (pKi values are ~5 at M1, M2, M3 and M4 receptors). Restores neurogenesis. Active in vivo.
Chemical name1-[4-(1-Pyrrolidinyl)-2-butyn-1-yl]-2-pyrrolidinone sesquifumarate
Storage instructionsStore at +4°C. The product can be stored for up to 12 months.
Solubility overviewSoluble in DMSO to 100 mM, in ethanol to 100 mM, in water to 25 mM and in PBS to 25 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab141079 has been referenced in 1 publication.
- Leroy F et al. Potassium currents dynamically set the recruitment and firing properties of F-type motoneurons in neonatal mice. J Neurophysiol 114:1963-73 (2015). PubMed: 26269551