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    oxr1-antibody-ab167012.pdf

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Cell Biology Other Antibodies Oxidative Stress
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Anti-OXR1 antibody (ab167012)

  • Datasheet
  • SDS
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-OXR1 antibody (ab167012)

    Key features and details

    • Rabbit polyclonal to OXR1
    • Suitable for: IHC-P
    • Reacts with: Human
    • Isotype: IgG

    You may also be interested in

    Secondary
    Product image
    Goat Anti-Rabbit IgG H&L (HRP) (ab205718)

    View more associated products

    Overview

    • Product name

      Anti-OXR1 antibody
      See all OXR1 primary antibodies
    • Description

      Rabbit polyclonal to OXR1
    • Host species

      Rabbit
    • Tested Applications & Species

      Application Species
      IHC-P
      Human
      See all applications and species data
    • Immunogen

      Synthetic peptide, corresponding to internal sequence amino acids of Human OXR1 (AAG25715.1).

    • Positive control

      • Human lung tissue.
    • General notes

      The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing the problem with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation.

      One factor contributing to the crisis is the use of antibodies that are not suitable. This can lead to misleading results and the use of incorrect data informing project assumptions and direction. To help address this challenge, we have introduced an application and species grid on our primary antibody datasheets to make it easy to simplify identification of the right antibody for your needs.

      Learn more here.

    Properties

    • Form

      Liquid
    • Storage instructions

      Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
    • Storage buffer

      pH: 7.40
      Preservative: 0.02% Sodium azide
      Constituents: 49% PBS, 50% Glycerol, 0.88% Sodium chloride

      PBS without Mg2+ and Ca2+
    • Concentration information loading...
    • Purity

      Immunogen affinity purified
    • Clonality

      Polyclonal
    • Isotype

      IgG
    • Research areas

      • Cell Biology
      • Other Antibodies
      • Oxidative Stress

    Associated products

    • Compatible Secondaries

      • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
      • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)
    • Isotype control

      • Rabbit IgG, polyclonal - Isotype Control (ChIP Grade) (ab171870)

    Applications

    The Abpromise guarantee

    Our Abpromise guarantee covers the use of ab167012 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Guaranteed

    Tested applications are guaranteed to work and covered by our Abpromise guarantee.

    Predicted

    Predicted to work for this combination of applications and species but not guaranteed.

    Incompatible

    Does not work for this combination of applications and species.

    Application Species
    IHC-P
    Human
    Application Abreviews Notes
    IHC-P
    Use a concentration of 5 µg/ml.
    Notes
    IHC-P
    Use a concentration of 5 µg/ml.

    Target

    • Function

      May be involved in protection from oxidative damage.
    • Sequence similarities

      Belongs to the OXR1 family.
      Contains 1 GRAM domain.
      Contains 1 LysM repeat.
      Contains 1 TLD domain.
    • Post-translational
      modifications

      Phosphorylated upon DNA damage, probably by ATM or ATR.
    • Cellular localization

      Mitochondrion.
    • Target information above from: UniProt accession Q8N573 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt
    • Database links

      • Entrez Gene: 55074 Human
      • Omim: 605609 Human
      • SwissProt: Q8N573 Human
      • Unigene: 127286 Human
      • Unigene: 740427 Human
      • Alternative names

        • C7 antibody
        • C7B antibody
        • Gm1238 antibody
        • Nbla00307 antibody
        • Nucleolar protein C7 antibody
        • Oxidation resistance 1 antibody
        • Oxidation resistance protein 1 antibody
        • Oxr1 antibody
        • OXR1_HUMAN antibody
        • Putative protein product of Nbla00307 antibody
        • rCG_59825 antibody
        see all

      Images

      • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-OXR1 antibody (ab167012)
        Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-OXR1 antibody (ab167012)
        Immunohistochemical analysis of formalin-fixed, paraffin embedded Human lung tissue labeling OXR1 with ab167012 at 5 µg/ml.

      Protocols

      • Immunohistochemistry protocols

      Click here to view the general protocols

      Datasheets and documents

      • SDS download

      • Datasheet download

        Download

      References (1)

      Publishing research using ab167012? Please let us know so that we can cite the reference in this datasheet.

      ab167012 has been referenced in 1 publication.

      • Jiang Y  et al. Serum secreted miR-137-containing exosomes affects oxidative stress of neurons by regulating OXR1 in Parkinson's disease. Brain Res 1722:146331 (2019). PubMed: 31301273

      Customer reviews and Q&As

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