Anti-OXSM antibody (ab154616)
Key features and details
- Rabbit polyclonal to OXSM
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-OXSM antibody
See all OXSM primary antibodies -
Description
Rabbit polyclonal to OXSM -
Host species
Rabbit -
Tested applications
Suitable for: WB, IHC-Pmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat, Cow -
Immunogen
Recombinant fragment, corresponding to a region within amino acids 1-276 of Human OXSM (Uniprot ID: Q9NWU1).
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Positive control
- HeLa whole cell lysate; Human hepatoma tissue.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 78.99% PBS, 1% BSA, 20% Glycerol (glycerin, glycerine) -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab154616 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/500 - 1/3000. Predicted molecular weight: 48 kDa.
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IHC-P |
1/100 - 1/1000.
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Notes |
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WB
1/500 - 1/3000. Predicted molecular weight: 48 kDa. |
IHC-P
1/100 - 1/1000. |
Target
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Function
May play a role in the biosynthesis of lipoic acid as well as longer chain fatty acids required for optimal mitochondrial function. -
Tissue specificity
Widely expressed. Higher expression in heart, skeletal muscle, liver and kidney which contain high levels of active mitochondria. -
Pathway
Lipid metabolism; fatty acid biosynthesis. -
Sequence similarities
Belongs to the beta-ketoacyl-ACP synthases family. -
Cellular localization
Mitochondrion. - Information by UniProt
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Database links
- Entrez Gene: 513530 Cow
- Entrez Gene: 54995 Human
- Entrez Gene: 71147 Mouse
- Entrez Gene: 289934 Rat
- Omim: 610324 Human
- SwissProt: Q0VCA7 Cow
- SwissProt: Q9NWU1 Human
- SwissProt: Q9D404 Mouse
see all -
Alternative names
- 3 oxoacyl ACP synthase, mitochondrial antibody
- 3 oxoacyl acyl carrier protein synthase antibody
- 3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial antibody
see all
Images
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (1)
ab154616 has been referenced in 1 publication.
- Gao T et al. Reduction of mitochondrial 3-oxoacyl-ACP synthase (OXSM) by hyperglycemia is associated with deficiency of a-lipoic acid synthetic pathway in kidney of diabetic mice. Biochem Biophys Res Commun 512:106-111 (2019). PubMed: 30871779