Overview

  • Product name

  • Description

    Rabbit polyclonal to OXSM
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Mouse, Human
    Predicted to work with: Rat
  • Immunogen

    Recombinant fragment within Human OXSM (internal sequence). The exact sequence is proprietary.
    Database link: Q9NWU1

  • Positive control

    • WB: A431, HeLa and HepG2 whole cell lysates. IHC-P: Human colon carcinoma tissue; Mouse muscle tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab229111 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 48 kDa.
IHC-P 1/100 - 1/1000.

Target

  • Function

    May play a role in the biosynthesis of lipoic acid as well as longer chain fatty acids required for optimal mitochondrial function.
  • Tissue specificity

    Widely expressed. Higher expression in heart, skeletal muscle, liver and kidney which contain high levels of active mitochondria.
  • Pathway

    Lipid metabolism; fatty acid biosynthesis.
  • Sequence similarities

    Belongs to the beta-ketoacyl-ACP synthases family.
  • Cellular localization

    Mitochondrion.
  • Information by UniProt
  • Database links

  • Alternative names

    • 3 oxoacyl ACP synthase, mitochondrial antibody
    • 3 oxoacyl acyl carrier protein synthase antibody
    • 3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial antibody
    • Acyl malonyl acyl carrier protein condensing enzyme antibody
    • Beta ketoacyl ACP synthase antibody
    • beta-ketoacyl synthase antibody
    • beta-ketoacyl synthase, mitochondrial antibody
    • Beta-ketoacyl-ACP synthase antibody
    • C80494 antibody
    • FASN2D antibody
    • FLJ20604 antibody
    • KASI antibody
    • KS antibody
    • OXSM antibody
    • OXSM_HUMAN antibody
    • type II mitochondrial beta ketoacyl synthase antibody
    see all

Images

  • All lanes : Anti-OXSM antibody (ab229111) at 1/1000 dilution

    Lane 1 : A431 (human epidermoid carcinoma cell line) whole cell lysate
    Lane 2 : HeLa (human epithelial cell line from cervix adenocarcinoma) whole cell lysate
    Lane 3 : HepG2 (human liver hepatocellular carcinoma cell line) whole cell lysate

    Lysates/proteins at 30 µg per lane.

    Predicted band size: 48 kDa



    10% SDS-PAGE gel.

  • Paraffin-embedded human colon carcinoma tissue stained for OXSM using ab229111 at 1/250 dilution in immunohistochemical analysis.

  • Paraffin-embedded human mouse muscle tissue stained for OXSM using ab229111 at 1/500 dilution in immunohistochemical analysis.

References

ab229111 has not yet been referenced specifically in any publications.

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