Oxymatrine (Matrine N-oxide), antiproliferative and apoptotic compound (ab143141)

Overview

  • Product name

    Oxymatrine (Matrine N-oxide), antiproliferative and apoptotic compound
  • Description

    Natural antiproliferative and apoptotic compound
  • Biological description

    Natural antiproliferative and apoptotic compound. Inhibits iNOS expression and TGF-β/Smad pathway in bleomycin-induced pulmonary fibrosis. Antitumor, antiviral and anti-arrhythmia agent. Active in vivo and in vitro.
  • CAS Number

    16837-52-8
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Liu L  et al. Oxymatrine attenuates bleomycin-induced pulmonary fibrosis in mice via the inhibition of inducible nitric oxide synthase expression and the TGF-ß/Smad signaling pathway. Int J Mol Med 29:815-22 (2012). Read more (PubMed: 22367596) »
  • Song G  et al. Effects of oxymatrine on proliferation and apoptosis in human hepatoma cells. Colloids Surf B Biointerfaces 48:1-5 (2006). Read more (PubMed: 16458489) »
  • Xiang X  et al. Effect of oxymatrine on murine fulminant hepatitis and hepatocyte apoptosis. Chin Med J (Engl) 115:593-6 (2002). Read more (PubMed: 12133306) »

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