Recombinant
RabMAb

Anti-Oxytocin-neurophysin 1 antibody [EPR4665] (ab124771)

This fast track antibody is not yet fully characterized. It is subject to these terms and conditions.

Overview

  • Product name
    Anti-Oxytocin-neurophysin 1 antibody [EPR4665]
    See all Oxytocin-neurophysin 1 primary antibodies
  • Description
    Rabbit monoclonal [EPR4665] to Oxytocin-neurophysin 1

    This product is a fast track antibody. It has been affinity purified and shows high titre values against the immunizing peptide by ELISA. Read the terms of use »

  • Host species
    Rabbit
  • Immunogen

    Synthetic peptide within Human Oxytocin-neurophysin 1 aa 1-100. The exact sequence is proprietary. The immunogen is within the oxytocin cleaved unit.
    Database link: P01178

  • General notes

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Fast track antibodies constitute a diverse group of products that have been released to accelerate your research, but are not yet fully characterized. They have all been affinity purified and show high titre values against the immunizing peptide (by ELISA). Fast track terms of use

Application Abreviews Notes
ELISA Use at an assay dependent dilution.

Target

  • Relevance
    Neurophysin 1 specifically binds oxytocin. Oxytocin causes contraction of the smooth muscle of the uterus and of the mammary gland. Oxytocin is a posterior pituitary hormone which is synthesized as an inactive precursor in the hypothalamus along with its carrier protein neurophysin I. Together with neurophysin, it is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis, where it is either stored or secreted into the bloodstream. Oxytocin contracts smooth muscle during parturition and lactation. It is also involved in cognition, tolerance, adaptation and complex sexual and maternal behaviour, as well as in the regulation of water excretion and cardiovascular functions.
  • Cellular localization
    Secreted
  • Alternative names
    • MGC126890 antibody
    • MGC126892 antibody
    • Neurophysin 1 antibody
    • Neurophysin I antibody
    • Ocytocin antibody
    • OT antibody
    • OT NPI antibody
    • OXT antibody
    • Oxytocin Neurophysin preproprotein antibody
    • Oxytocin prepro (neurophysin I) antibody
    • Oxytocin prepropeptide antibody
    • Oxytocin-neurophysin 1 antibody
    see all

Images

This Fast-Track antibody is not yet fully characterised. These images represent inconclusive preliminary data.

  • ELISA image demonstrating the relationship between the concentration of antibody and optical density readings.

References

ab124771 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

1-3 of 3 Abreviews or Q&A

Answer

Oxytocin is a peptide of nine amino acids, which this antibody is designed to detect. The characterization of this antibody is based on the peptide and our ELISA data (we have not tested it for any other applications). At this time we can only recommend it for detection of the 9 amino acid peptide, not the 125 amino acid precursor molecule.

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Answer

Thank you for your reply. I am very pleased to hear you would like to accept our offer and test ab78364 with ab124771 in sandwich ELISA.

To confirm, the discount code is valid for 4 months, the Abreview needs to be submitted and the order placed for the free of charge antibody before this expiry date. The order can go through our Australian distributor Sapphire Biosciences. I am copying them into this email so they are aware.

DISCOUNT CODE: 40801
Expiration date:4th Jan 2013

This code will give you: 1 free primary antibody before the expiration date. To redeem this offer, please submit an Abreview for ab78364 with ab124771in sandwich ELISA. and include this code in the “Additional Comments” section so we know the Abreview is for this promotion. Please remember that submission of the Abreview is sufficient for the discount code to become active.

For more information on how to submit an Abreview, please visit the site: www.abcam.com/Abreviews.

Remember, we publish both positive and negative Abreviews on our datasheets so please submit the results of your tests. The code will be active once the Abreview has been submitted and can be redeemed in one of the following ways: 1) Call to place your order and mention the code to our customer service department; 2) Include the code in your fax order; 3) Place your order on the web and enter the promotional code.

With regards to your questions regarding concentration and volume:

ab78364 Anti-Oxytocin antibody [4G11]
The volume is provided on the datasheet, 100 ul
I am sorry the concentration will not be determined as this is sold as ascites fluid.

ab124771 Anti-Oxytocin antibody [EPR4665]
The volume is on the datasheet, 100 ul
I am sorry the concentration will not be determiend as this is sold as tissue culture supernatant, concentration not determined.

Unpurified antibodies, such as those sold as whole antiserum, ascites or tissue culture supernatant will not have a concentration stated on the datasheet. Antibody concentration is usually determined by protein assay, and serum / ascites / tissue culture supernatant will contain a lot of other proteins, which means the antibody quantification would not be accurate. I can confirm that for ascites, concentration of antibody is known to very between 5 - 10 mg/ml. I can confirm that for tissue culture supernatant, concentration of antibody is known to very betwen 1 - 3 mg/ml. I am sorry we are not able to provide an exact concentration on this occasion.

Any feedback that you can provide regarding your sELISA experiments will be greatly appreciated, whether positive or negative. If you have any further questions, please do not hesitate to contact us. We look forward to receiving your Abreview and wish you luck with your research.

The terms and conditions applicable to this offer can be found here: www.abcam.com/collaborationdiscount.

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Answer

Thank you very much for your enquiry.

To our knowledge, I as sorry to confirm that ab124771 and ab78364 havenot been tested and aer not covered by our 6 month guarantee insandwich ELISA (sELISA). Therefore, I can offer a discount off a future purchase if you buythese antibodiesnow, test them insELISA and submit feedback to us in the form of an Abreview. It doesn’t matter whether the Abreview is positive or negative, we would just really like to receive your feedback. The discount would be to the value of: 1 free primary antibody.

If you are interested in this offer, please follow these steps:

1. Reply to this e-mail to let me know that you would like to proceed and test ab124771 and ab78364 in sELISA. I will then send a discount code. This code must be issued before purchasingab124771 and ab78364 so please wait for my reply before ordering.

2. Purchaseab124771 and ab78364 either by phone, fax, or online (https://www.abcam.com).This initial purchase will be at full price.

3. Test them in sELISA.

4. Let us know the results, positive or negative, using our Abreview system (this will take about 10 minutes and images are great if you have them!). To find out how to submit an Abreview, please visit: https://www.abcam.com/abreviews. You can submit one Abreview from the datasheet of either ab124771or ab78364

5. After the review is submitted to us, the discount code becomes active. Simply place your new order by phone, fax, or on the web and mention the discount code. The discount can be redeemed for any primary antibody ordered and the discount code is valid for 4 months after issue.

Please remember that submission of the Abreview is sufficient for the discount code to become active.

We are always pleased to obtain feedback about our products and any information is greatly appreciated! Even if ab124771 and ab78364 turns out to be unsuitable for sELISA, you will still receive the discount on your next purchase after your Abreview has been submitted.

Please let me know if you have any questions about this offer and I would be happy to help you further.

The Terms and Conditions of this offer can be found at: www.abcam.com/collaborationdiscount.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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