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  1. Link

    p-nitrobenzyl-mesylate-alkylation-reagent-ab138910.pdf

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Biochemicals Chemical Type Biochemicals
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p-Nitrobenzyl mesylate, Alkylation reagent (ab138910)

  • Datasheet
  • COA
Submit a review Q&A (1)References (39)

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Key features and details

  • Alkylation reagent
  • CAS Number: 39628-94-9
  • Soluble in DMSO to 100 mM
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    p-Nitrobenzyl mesylate, Alkylation reagent
  • Description

    Alkylation reagent
  • Biological description

    An alkylation reagent to be used with ab92570 rabbit monoclonal anti-thiophosphate ester antibody and ab138911 ATP-gamma-S for the identification of direct kinase substrates.

    Prepare a 50 mM PNBM (12 mg/ml) stock by dissolving PNBM in DMSO and vortexing.

    One time use DMSO aliquots may be stored at -20°C.

  • CAS Number

    39628-94-9
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    4-Nitrobenzyl mesylate
  • Molecular weight

    231.22
  • Molecular formula

    C8H9NO5S
  • PubChem identifier

    18924794
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO to 100 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CS(=O)(=O)OCC1=CC=C(C=C1)[N+](=O)[O-]
  • Source

    Synthetic

  • Research areas

    • Biochemicals
    • Chemical Type
    • Biochemicals
    • Biochemicals
    • Pharmacology
    • Signaling
    • DNA, RNA & protein synthesis
    • Protein synthesis

Applications

The Abpromise guarantee

Our Abpromise guarantee covers the use of ab138910 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Functional Studies
Use at an assay dependent concentration.
Notes
Functional Studies
Use at an assay dependent concentration.

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

Datasheets and documents

  • Datasheet download

    Download
  • COA

References (39)

Publishing research using ab138910? Please let us know so that we can cite the reference in this datasheet.

ab138910 has been referenced in 39 publications.

  • Nikalayevich E  et al. Aurora B/C-dependent phosphorylation promotes Rec8 cleavage in mammalian oocytes. Curr Biol 32:2281-2290.e4 (2022). PubMed: 35385691
  • Yu B  et al. SUMO proteases SENP3 and SENP5 spatiotemporally regulate the kinase activity of Aurora A. J Cell Sci 134:N/A (2021). PubMed: 34313310
  • Ryzhakov G  et al. Defactinib inhibits PYK2 phosphorylation of IRF5 and reduces intestinal inflammation. Nat Commun 12:6702 (2021). PubMed: 34795257
  • Zhang H  et al. A subcellular map of the human kinome. Elife 10:N/A (2021). PubMed: 33988507
  • Lin Z  et al. Initiation and amplification of SnRK2 activation in abscisic acid signaling. Nat Commun 12:2456 (2021). PubMed: 33911084
View all Publications for this product

Customer reviews and Q&As

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Submit a review Submit a question

Question

EPITOMICS Produkt: p-nitrobenzyl mesylate (PNBM) Cat.#: 3700-1

Read More

Abcam community

Verified customer

Asked on Sep 11 2012

Answer

Vielen Dank für Ihren Anruf und ihre Geduld.

Ich freue mich Ihnen mitteilen zu können, dass p-nitrobenzyl mesylate (PNBM) Cat.#: 3700-1 von Epitomics auch weiterhin erhältlich sein wird.

Die neue Abcam Artikelnummer lautet:

ab138910

https://www.abcam.com/p-Nitrobenzyl-mesylate-Alkylation-reagent-ab138910.html (or use the following: https://www.abcam.com/p-Nitrobenzyl-mesylate-Alkylation-reagent-ab138910.html).

Wir freuen uns auf Ihre Bestellung und wünschen Ihnen viel Erfolg mit Ihrer Forschung. Bitte zögern Sie nicht, mich nochmals zu kontaktieren, falls Sie weitere Fragen haben.

Read More

Abcam Scientific Support

Answered on Sep 11 2012

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
For licensing inquiries, please contact partnerships@abcam.com

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