Anti-ARPC5/p16 ARC antibody (ab151303)
Key features and details
- Rabbit polyclonal to ARPC5/p16 ARC
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
Get better batch-to-batch reproducibility with a recombinant antibody
- Research with confidence – consistent and reproducible results with every batch
- Long-term and scalable supply – powered by recombinant technology for fast production
- Success from the first experiment – confirmed specificity through extensive validation
- Ethical standards compliant – production is animal-free
Overview
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Product name
Anti-ARPC5/p16 ARC antibody
See all ARPC5/p16 ARC primary antibodies -
Description
Rabbit polyclonal to ARPC5/p16 ARC -
Host species
Rabbit -
Specificity
This antibody is specific to the p16 ARC protein, database link: O15511. There is no observed cross reactivity to the CDKN2A/p16INK4a protein.
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Tested applications
Suitable for: WB, IHC-Pmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat, Chicken, Cow, Pig -
Immunogen
Recombinant fragment corresponding to Human ARPC5/p16 ARC aa 1-200.
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Positive control
- THP1 and HL60 cells lysates; Colon cancer tissue
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.00
Preservative: 0.025% Proclin 300
Constituents: 79% PBS, 20% Glycerol (glycerin, glycerine) -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab151303 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/500 - 1/3000. Predicted molecular weight: 16 kDa.
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IHC-P |
1/100 - 1/1000.
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Notes |
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WB
1/500 - 1/3000. Predicted molecular weight: 16 kDa. |
IHC-P
1/100 - 1/1000. |
Target
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Function
Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. -
Sequence similarities
Belongs to the ARPC5 family. -
Cellular localization
Cytoplasm > cytoskeleton. Cell projection. - Information by UniProt
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Database links
- Entrez Gene: 429075 Chicken
- Entrez Gene: 614345 Cow
- Entrez Gene: 10092 Human
- Entrez Gene: 67771 Mouse
- Entrez Gene: 100174965 Pig
- Entrez Gene: 360854 Rat
- Omim: 604227 Human
- SwissProt: Q3SYX9 Cow
see all -
Alternative names
- Actin related protein 2/3 complex subunit 5 (16 kD) antibody
- Actin related protein 2/3 complex subunit 5 antibody
- Actin related protein 2/3 complex, subunit 5 16kDa antibody
see all
Images
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All lanes : Anti-ARPC5/p16 ARC antibody (ab151303) at 1/500 dilution
Lane 1 : THP1 whole cell lysate
Lane 2 : HL60 whole cell lysate
Lysates/proteins at 30 µg per lane.
Predicted band size: 16 kDa
15% SDS PAGE -
Immunohistochemical analysis of paraffin-embedded Human colon cancer labeling p16 ARC with ab151303 antibody at 1/500 dilution.
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (15)
ab151303 has been referenced in 15 publications.
- Cheng X et al. Construction and Verification of Immunohistochemistry Parameters-Based Classifier to Predict Local-Recurrence of Upper Tract Urothelial Carcinoma After Kidney-Sparing Surgery. Front Oncol 12:872432 (2022). PubMed: 35600373
- Tian X et al. Inhibition of DEK Enhances Doxorubicin-Induced Apoptosis and Cell Cycle Arrest in T-Cell Acute Lymphoblastic Leukemia Cells. Dis Markers 2022:9312971 (2022). PubMed: 35769815
- Jiang H et al. MicroRNA-338-3p as a novel therapeutic target for intervertebral disc degeneration. Exp Mol Med 53:1356-1365 (2021). PubMed: 34531509
- Luo R et al. FAM134B-Mediated ER-phagy Upregulation Attenuates AGEs-Induced Apoptosis and Senescence in Human Nucleus Pulposus Cells. Oxid Med Cell Longev 2021:3843145 (2021). PubMed: 34394825
- Ge R et al. Upregulated microRNA-126 induces apoptosis of dental pulp stem cell via mediating PTEN-regulated Akt activation. J Clin Lab Anal 35:e23624 (2021). PubMed: 33150661