• Product name
  • Description
    Rabbit polyclonal to P2RY5
  • Host species
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse
    Predicted to work with: Human
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to a region within internal sequence amino acids 113-142 of Human P2RY5 (NP_001155969.1, NP_005758.2, NP_001155970.1).

  • Positive control
    • Mouse heart tissue lysates


  • Form
  • Storage instructions
    Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
  • Storage buffer
    Preservative: 0.09% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Purification notes
    ab113055 was purified through a protein A column, followed by peptide affinity purification.
  • Clonality
  • Isotype
  • Research areas


Our Abpromise guarantee covers the use of ab113055 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 39 kDa.


  • Function
    Binds to oleoyl-L-alpha-lysophosphatidic acid (LPA). Intracellular cAMP is involved in the receptor activation. Important for the maintenance of hair growth and texture.
  • Tissue specificity
    Expressed ubiquitously, including in skin and hair follicle cells. Detected in both Henle's and Huxley's layers of the inner root sheath of the hair follicle and in suprabasal layers of the epidermis (at protein level). Expressed at low levels in peripheral blood leukocytes.
  • Involvement in disease
    Defects in LPAR6 are the cause of woolly hair autosomal recessive type 1 (ARWH1) [MIM:278150]. A hair shaft disorder characterized by fine and tightly curled hair. Compared to normal curly hair that is observed in some populations, woolly hair grows slowly and stops growing after a few inches. Under light microscopy, woolly hair shows some structural anomalies, including trichorrexis nodosa and tapered ends.
    Defects in LPAR6 are the cause of hypotrichosis localized autosomal recessive type 3 (LAH3) [MIM:611452]. A condition characterized by the presence of less than the normal amount of hair. Affected individuals show progressive hair loss, thinning of scalp hair since early childhood, sparse body hair, and sparse eyebrows and eyelashes in some cases.
  • Sequence similarities
    Belongs to the G-protein coupled receptor 1 family.
  • Developmental stage
    Markedly up-regulated in promyelocytic HL60 cells induced to differentiate along the monocyte/macrophage pathway. Not detectable in undifferentiated HL60 cells and only low levels after the induction of differentiation along the granulocytic pathway.
  • Cellular localization
    Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • ARWH1 antibody
    • G protein coupled purinergic receptor P2Y5 antibody
    • LAH 3 antibody
    • LAH3 antibody
    • LPA receptor 6 antibody
    • LPA-6 antibody
    • LPAR 6 antibody
    • Lpar6 antibody
    • LPAR6_HUMAN antibody
    • Lysophosphatidic acid receptor 6 antibody
    • MGC 120358 antibody
    • MGC120358 antibody
    • Oleoyl L alpha lysophosphatidic acid receptor antibody
    • Oleoyl-L-alpha-lysophosphatidic acid receptor antibody
    • P 2 RY 5 antibody
    • p2ry5 antibody
    • P2Y purinoceptor 5 antibody
    • P2Y5 antibody
    • Purinergic receptor 5 antibody
    • purinergic receptor P2Y, G protein coupled, 5 antibody
    • purinergic receptor p2y5 antibody
    • RB intron encoded G protein coupled receptor antibody
    • RB intron encoded G-protein coupled receptor antibody
    see all


  • Anti-P2RY5 antibody (ab113055) at 1/100 dilution + Mouse heart tissue lysates at 35 µg

    Predicted band size: 39 kDa


This product has been referenced in:
  • Brünnert D  et al. Lysophosphatidic acid and sphingosine 1-phosphate metabolic pathways and their receptors are differentially regulated during decidualization of human endometrial stromal cells. Mol Hum Reprod N/A:N/A (2014). Read more (PubMed: 24994816) »

See 1 Publication for this product

Customer reviews and Q&As

The lysates that were used to validate the two P2RY5 antibodies for western blotting are not available for sale, but we at least have a lysate that is equivalent to the mouse heart lysate that was used in the blot shown on the ab113055 datasheet. The c...

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