Key features and details
- Guinea pig polyclonal to P2X2
- Suitable for: IHC-Fr, WB, IHC-FoFr
- Reacts with: Rat, Human
- Isotype: IgG
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage bufferPreservative: 0.05% Sodium azide
Constituent: Whole serum
Concentration information loading...
Our Abpromise guarantee covers the use of ab10262 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500. Predicted molecular weight: 47.8 kDa.|
|IHC-FoFr||Use at an assay dependent concentration. PubMed: 20620196|
FunctionIon channel gated by extracellular ATP involved in a variety of cellular responses, such as excitatory postsynaptic responses in sensory neurons, neuromuscular junctions (NMJ) formation, hearing, perception of taste and peristalsis. In the inner ear, regulates sound transduction and auditory neurotransmission, outer hair cell electromotility, inner ear gap junctions, and K(+) recycling. Mediates synaptic transmission between neurons and from neurons to smooth muscle.
Involvement in diseaseDeafness, autosomal dominant, 41
Sequence similaritiesBelongs to the P2X receptor family.
Cellular localizationCell membrane. Localizes to the apical membranes of hair cells in the organ of Corti.
- Information by UniProt
FormThere are 7 isoforms produced by alternative splicing.
- ATP receptor antibody
- MGC129601 antibody
- P2RX 2 antibody
ab10262 has been referenced in 1 publication.
- Bjelobaba I et al. The cortical stab injury induces beading of fibers expressing ecto-nucleoside triphosphate diphosphohydrolase 3. Neuroscience 170:107-16 (2010). IHC-FoFr ; Rat . PubMed: 20620196