• Product name

  • Description

    Rabbit polyclonal to P2X2
  • Host species

  • Tested applications

    Suitable for: WB, IHC-Fr, ICC, IHC-FoFr, IHC-Pmore details
  • Species reactivity

    Reacts with: Rat, Human
    Predicted to work with: Mouse, Guinea pig, Non human primates
  • Immunogen

    Synthetic peptide:


    , corresponding to amino acids 460-472 of Rat P2X2.



Our Abpromise guarantee covers the use of ab10266 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000. Predicted molecular weight: 47,8 kDa.
IHC-Fr 1/1000.
ICC 1/1000.
IHC-FoFr Use at an assay dependent concentration.
IHC-P Use at an assay dependent concentration. PubMed: 21969132


  • Function

    Ion channel gated by extracellular ATP involved in a variety of cellular responses, such as excitatory postsynaptic responses in sensory neurons, neuromuscular junctions (NMJ) formation, hearing, perception of taste and peristalsis. In the inner ear, regulates sound transduction and auditory neurotransmission, outer hair cell electromotility, inner ear gap junctions, and K(+) recycling. Mediates synaptic transmission between neurons and from neurons to smooth muscle.
  • Involvement in disease

    Deafness, autosomal dominant, 41
  • Sequence similarities

    Belongs to the P2X receptor family.
  • Cellular localization

    Cell membrane. Localizes to the apical membranes of hair cells in the organ of Corti.
  • Information by UniProt
  • Database links

  • Form

    There are 7 isoforms produced by alternative splicing.
  • Alternative names

    • ATP receptor antibody
    • MGC129601 antibody
    • P2RX 2 antibody
    • P2RX2 antibody
    • P2RX2_HUMAN antibody
    • P2X purinoceptor 2 antibody
    • P2X Receptor subunit 2 antibody
    • P2X2 antibody
    • P2X2a antibody
    • Purinergic receptor antibody
    • Purinergic receptor P2X ligand gated ion channel 2 antibody
    • Purinergic receptor P2X2 isoform A antibody
    • Purinergic receptor P2X2 isoform B antibody
    • Purinergic receptor P2X2 isoform C antibody
    • Purinergic receptor P2X2 isoform D antibody
    • Purinergic receptor P2X2 isoform H antibody
    • Purinergic receptor P2X2 isoform I antibody
    see all


  • ab10266, at a dilution of 1/1000, staining P2X2 in rat brain stem by Immunohistochemistry (PFA perfusion fixed frozen sections).


This product has been referenced in:

  • Solís-Chagoyán H  et al. Purinergic Signaling Pathway in Human Olfactory Neuronal Precursor Cells. Stem Cells Int 2019:2728786 (2019). Read more (PubMed: 31065271) »
  • Wu KC  et al. I-Tiao-Gung extract through its active component daidzin improves cyclophosphamide-induced bladder dysfunction in rat model. Neurourol Urodyn 37:2560-2570 (2018). Read more (PubMed: 30252154) »
See all 5 Publications for this product

Customer reviews and Q&As

1-4 of 4 Abreviews or Q&A


Thank you for your inquiry.

As you correctly suspected, we do not know the concentration of the antibody.

Antibody concentration is usually measured by measuring the protein content. Since there are many different proteins in whole antiserum, it is not possible to find out the concentration of one specific antibody.

As a general estimate, we assume a concentration of 1 to 10mg/ml for the specific antibody.

I hope this information will be helpful to your customer.

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Thank you for your inquiry. To our knowledge, ab10266 has not yet been tested in flow cytometry. It is possible that this product may be suitable for your experiment since it has been successfully used in ICC, but we don't have any data regarding its use in flow cytometry so we cannot guarantee its use in this way. Because this antibody recognizes a cytoplasmic domain of P2X2, you will need to fix and permeabilize the cells when using this antibody. We do have a P2X2 antibody that recognizes an extracellular domain, which is ab48864. This also has not been tested in flow cytometry, but may be able to be used with unfixed cells. I've included a link at the bottom of this email to the product for your convenience. If you are interested in testing either of these and sharing your data with us, we may be able to offer our testing discount. Please let me know if you are interested. Best of luck in your research!

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Thank you for your enquiry. Antibodies ab10262 and ab10266 are raised against the same peptide which, according to the map found at the link to the SwissProt entry with accession number P49653, is found on a cytoplasmic domain of the protein. I hope this helps. Please do not hesitate to contact us if you have any other questions.

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Thank you for your enquiry and for your patience. The epitopes are intracellular for both ab10266 and ab10267. So unfortunately, they will not suit your needs. If you have any more questions, please contact us again.

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