Key features and details
- Rabbit polyclonal to P2X2
- Suitable for: IHC-P, WB
- Reacts with: Mouse, Human
- Isotype: IgG
Product nameAnti-P2X2 antibody
See all P2X2 primary antibodies
DescriptionRabbit polyclonal to P2X2
Tested applicationsSuitable for: IHC-P, WBmore details
Species reactivityReacts with: Mouse, Human
Recombinant fragment within Human P2X2 (internal sequence). The exact sequence is proprietary.
Database link: Q9UBL9
- WB: HepG2 whole cell lysate (ab7900) and mouse brain tissue extract. IHC-P: Human breast cancer tissue.
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Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 78.99% PBS, 1% BSA, 20% Glycerol (glycerin, glycerine)
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab229151 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||1/100 - 1/1000.|
|WB||1/500 - 1/3000. Predicted molecular weight: 52 kDa.|
FunctionIon channel gated by extracellular ATP involved in a variety of cellular responses, such as excitatory postsynaptic responses in sensory neurons, neuromuscular junctions (NMJ) formation, hearing, perception of taste and peristalsis. In the inner ear, regulates sound transduction and auditory neurotransmission, outer hair cell electromotility, inner ear gap junctions, and K(+) recycling. Mediates synaptic transmission between neurons and from neurons to smooth muscle.
Involvement in diseaseDeafness, autosomal dominant, 41
Sequence similaritiesBelongs to the P2X receptor family.
Cellular localizationCell membrane. Localizes to the apical membranes of hair cells in the organ of Corti.
- Information by UniProt
FormThere are 7 isoforms produced by alternative splicing.
- ATP receptor antibody
- MGC129601 antibody
- P2RX 2 antibody
Anti-P2X2 antibody (ab229151) at 1/1000 dilution + HepG2 (human liver hepatocellular carcinoma cell line) whole cell lysate at 30 µg
Predicted band size: 52 kDa
Paraffin-embedded human breast cancer tissue stained for P2X2 using ab229151 at 1/500 dilution in immunohistochemical analysis.
Anti-P2X2 antibody (ab229151) at 1/500 dilution + Mouse brain tissue extract at 50 µg
Predicted band size: 52 kDa
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab229151 has not yet been referenced specifically in any publications.