Overview

  • Product name

  • Description

    Rabbit polyclonal to P2X2
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-P, WBmore details
  • Species reactivity

    Reacts with: Mouse, Human
  • Immunogen

    Recombinant fragment within Human P2X2 (internal sequence). The exact sequence is proprietary.
    Database link: Q9UBL9

  • Positive control

    • WB: HepG2 whole cell lysate (ab7900) and mouse brain tissue extract. IHC-P: Human breast cancer tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab229151 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/100 - 1/1000.
WB 1/500 - 1/3000. Predicted molecular weight: 52 kDa.

Target

  • Function

    Ion channel gated by extracellular ATP involved in a variety of cellular responses, such as excitatory postsynaptic responses in sensory neurons, neuromuscular junctions (NMJ) formation, hearing, perception of taste and peristalsis. In the inner ear, regulates sound transduction and auditory neurotransmission, outer hair cell electromotility, inner ear gap junctions, and K(+) recycling. Mediates synaptic transmission between neurons and from neurons to smooth muscle.
  • Involvement in disease

    Deafness, autosomal dominant, 41
  • Sequence similarities

    Belongs to the P2X receptor family.
  • Cellular localization

    Cell membrane. Localizes to the apical membranes of hair cells in the organ of Corti.
  • Information by UniProt
  • Database links

  • Form

    There are 7 isoforms produced by alternative splicing.
  • Alternative names

    • ATP receptor antibody
    • MGC129601 antibody
    • P2RX 2 antibody
    • P2RX2 antibody
    • P2RX2_HUMAN antibody
    • P2X purinoceptor 2 antibody
    • P2X Receptor subunit 2 antibody
    • P2X2 antibody
    • P2X2a antibody
    • Purinergic receptor antibody
    • Purinergic receptor P2X ligand gated ion channel 2 antibody
    • Purinergic receptor P2X2 isoform A antibody
    • Purinergic receptor P2X2 isoform B antibody
    • Purinergic receptor P2X2 isoform C antibody
    • Purinergic receptor P2X2 isoform D antibody
    • Purinergic receptor P2X2 isoform H antibody
    • Purinergic receptor P2X2 isoform I antibody
    see all

Images

  • Anti-P2X2 antibody (ab229151) at 1/1000 dilution + HepG2 (human liver hepatocellular carcinoma cell line) whole cell lysate at 30 µg

    Predicted band size: 52 kDa



    10% SDS-PAGE

  • Paraffin-embedded human breast cancer tissue stained for P2X2 using ab229151 at 1/500 dilution in immunohistochemical analysis.

  • Anti-P2X2 antibody (ab229151) at 1/500 dilution + Mouse brain tissue extract at 50 µg

    Predicted band size: 52 kDa



    10% SDS-PAGE

References

ab229151 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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