Anti-P2Y11 antibody - C-terminal (ab183096)
Key features and details
- Rabbit polyclonal to P2Y11 - C-terminal
- Suitable for: IHC-P, WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-P2Y11 antibody - C-terminal
See all P2Y11 primary antibodies -
Description
Rabbit polyclonal to P2Y11 - C-terminal -
Host species
Rabbit -
Tested applications
Suitable for: IHC-P, WBmore details -
Species reactivity
Reacts with: Human -
Immunogen
Synthetic peptide within Human P2Y11 aa 361-374 (C terminal). The exact sequence is proprietary. (NP_002557).
Sequence:APKPSEPQSRELSQ
Database link: Q96G91 -
Positive control
- Hela and 293T cell lysates; Human lung cancer tissue.
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General notes
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.4
Preservative: 0.05% Sodium azide
Constituents: 50% Glycerol (glycerin, glycerine), 49% PBS
Note: PBS without Mg2+ and Ca2+. -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
Applications
Our Abpromise guarantee covers the use of ab183096 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
IHC-P | 1/25 - 1/100. | |
WB | 1/200 - 1/1000. Predicted molecular weight: 40 kDa. |
Target
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Function
Receptor for ATP and ADP coupled to G-proteins that activate both phosphatidylinositol-calcium and adenylyl cyclase second messenger systems. Not activated by UTP or UDP. -
Tissue specificity
Highest expression in liver and spleen. -
Sequence similarities
Belongs to the G-protein coupled receptor 1 family. -
Cellular localization
Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 5032 Human
- Omim: 602697 Human
- SwissProt: Q96G91 Human
- Unigene: 14468 Human
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Alternative names
- P2RY11 antibody
- P2Y purinoceptor 11 antibody
- P2Y11 antibody
see all
Images
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All lanes : Anti-P2Y11 antibody - C-terminal (ab183096) at 1/500 dilution
Lane 1 : HeLa cell lysate
Lane 2 : 293T cell lysate
Lysates/proteins at 40 µg per lane.
Secondary
All lanes : Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution
Developed using the ECL technique.
Predicted band size: 40 kDa
Exposure time: 1 minute -
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-P2Y11 antibody - C-terminal (ab183096)
Immunohistochemical analysis of paraffin-embedded Human lung cancer tissue labeling P2Y11 with ab183096 at 1/40 dilution, in the presence (right panel) or absence (left panel) of immunizing peptide.
Protocols
Datasheets and documents
References (1)
ab183096 has been referenced in 1 publication.
- Dreisig K et al. Human P2Y11 Expression Level Affects Human P2X7 Receptor-Mediated Cell Death. Front Immunol 9:1159 (2018). PubMed: 29937766