Anti-P2Y14 antibody (ab136264)

Submit a review Submit a question References (2)
Western blot - Anti-P2Y14 antibody (ab136264)

    Key features and details

    • Rabbit polyclonal to P2Y14
    • Suitable for: WB
    • Reacts with: Human
    • Isotype: IgG

    Overview

    • Product name

      Anti-P2Y14 antibody
      See all P2Y14 primary antibodies

    • Description

      Rabbit polyclonal to P2Y14

    • Host species

      Rabbit

    • Tested applications

      Suitable for: WBmore details

    • Species reactivity

      Reacts with: Human
      Predicted to work with: Mouse, Rat

    • Immunogen

      Synthetic peptide corresponding to Human P2Y14 (internal sequence).

    • Positive control

      • K562 cell lysate.

    • General notes

      Previously labelled as GPCR GPR105. 

      Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.

      Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.

      We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.

      In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.

      We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.

      Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.

      Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.

    Properties

    • Form

      Liquid

    • Storage instructions

      Shipped at 4°C. Store at -20ºC.

    • Storage buffer

      pH: 7.40
      Preservative: 0.02% Sodium azide
      Constituents: 49% PBS, 0.88% Sodium chloride, 50% Glycerol (glycerin, glycerine)

      PBS is without Mg2+ and Ca2+.
    • Concentration information loading...

    • Purity

      Immunogen affinity purified

    • Purification notes

      ab136264 was affinity-purified from rabbit antiserum by immunogenic peptide affinity-chromatography.

    • Clonality

      Polyclonal

    • Isotype

      IgG

    • Research areas

    Applications

    Our Abpromise guarantee covers the use of ab136264 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Abreviews Notes
    WB 1/500 - 1/1000. Predicted molecular weight: 39 kDa.

    Target

    • Function

      Receptor for UDP-glucose and other UDP-sugar coupled to G-proteins. Not activated by ATP, ADP, UTP or ATP.

    • Tissue specificity

      Highest expression in the placenta, adipose tissue, stomach and intestine, intermediate levels in the brain, spleen, lung and heart, lowest levels in the kidney.

    • Sequence similarities

      Belongs to the G-protein coupled receptor 1 family.

    • Cellular localization

      Cell membrane.
    • Information by UniProt

    • Database links

      see all

    • Alternative names

      • A330108O13Rik antibody
      • G protein coupled receptor for UDP-glucose antibody
      • G protein-coupled receptor 105 antibody
      • G protein-coupled receptor VTR 15-20 antibody
      • G-protein coupled receptor 105 antibody
      • GPCR GPR105 antibody
      • GPR105 antibody
      • KIAA0001 antibody
      • P2RY14 antibody
      • P2Y purinoceptor 14 antibody
      • P2Y(14) receptor antibody
      • P2Y14 antibody
      • P2Y14 receptor antibody
      • P2Y14_HUMAN antibody
      • Purinergic receptor P2Y G protein coupled 14 antibody
      • Similar to TYPE-1 Angiotensin II receptor antibody
      • UDP-glucose receptor antibody
      see all

    Images

    • Western blot - Anti-P2Y14 antibody (ab136264)
      Western blot - Anti-P2Y14 antibody (ab136264)
      Anti-P2Y14 antibody (ab136264) at 1/500 dilution + K562 cell lysate at 30 µg

      Predicted band size: 39 kDa

    References (2)

    Publishing research using ab136264? Please let us know so that we can cite the reference in this datasheet.

    ab136264 has been referenced in 2 publications.

    • Ma J  et al. Glycogen metabolism regulates macrophage-mediated acute inflammatory responses. Nat Commun 11:1769 (2020). PubMed: 32286295
    • Haanes KA & Edvinsson L Characterization of the contractile P2Y14 receptor in mouse coronary and cerebral arteries. FEBS Lett 588:2936-43 (2014). PubMed: 24911208

    Customer reviews and Q&As

    Show All Reviews Q&A
    Submit a review Submit a question

    There are currently no Customer reviews or Questions for ab136264.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com