Anti-P2Y14 antibody (ab136264)
Key features and details
- Rabbit polyclonal to P2Y14
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-P2Y14 antibody
See all P2Y14 primary antibodies -
Description
Rabbit polyclonal to P2Y14 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat -
Immunogen
Synthetic peptide corresponding to Human P2Y14 (internal sequence).
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Positive control
- K562 cell lysate.
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General notes
Previously labelled as GPCR GPR105.
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at -20ºC. -
Storage buffer
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 49% PBS, 0.88% Sodium chloride, 50% Glycerol (glycerin, glycerine)
PBS is without Mg2+ and Ca2+. -
Concentration information loading...
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Purity
Immunogen affinity purified -
Purification notes
ab136264 was affinity-purified from rabbit antiserum by immunogenic peptide affinity-chromatography. -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
Our Abpromise guarantee covers the use of ab136264 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB | 1/500 - 1/1000. Predicted molecular weight: 39 kDa. |
Target
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Function
Receptor for UDP-glucose and other UDP-sugar coupled to G-proteins. Not activated by ATP, ADP, UTP or ATP. -
Tissue specificity
Highest expression in the placenta, adipose tissue, stomach and intestine, intermediate levels in the brain, spleen, lung and heart, lowest levels in the kidney. -
Sequence similarities
Belongs to the G-protein coupled receptor 1 family. -
Cellular localization
Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 9934 Human
- Entrez Gene: 140795 Mouse
- Entrez Gene: 171108 Rat
- Omim: 610116 Human
- SwissProt: Q15391 Human
- SwissProt: Q9ESG6 Mouse
- SwissProt: O35881 Rat
- Unigene: 2465 Human
see all -
Alternative names
- A330108O13Rik antibody
- G protein coupled receptor for UDP-glucose antibody
- G protein-coupled receptor 105 antibody
see all
Images
Datasheets and documents
References (2)
ab136264 has been referenced in 2 publications.
- Ma J et al. Glycogen metabolism regulates macrophage-mediated acute inflammatory responses. Nat Commun 11:1769 (2020). PubMed: 32286295
- Haanes KA & Edvinsson L Characterization of the contractile P2Y14 receptor in mouse coronary and cerebral arteries. FEBS Lett 588:2936-43 (2014). PubMed: 24911208