Overview

  • Product name

    Anti-p39 antibody [EPR5074]
    See all p39 primary antibodies
  • Description

    Rabbit monoclonal [EPR5074] to p39
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IP, IHC-Pmore details
    Unsuitable for: Flow Cyt or ICC
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide within p39. The exact sequence is proprietary.

  • Positive control

    • Human brain tissue; Human fetal brain, Mouse brain, Rat brain and SH-SY5Y lysates.
  • General notes

     

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • Storage buffer

    pH: 7.40
    Preservative: 0.05% Sodium azide
    Constituents: 0.1% BSA, 40% Glycerol, 9.85% Tris glycine, 50% Tissue culture supernatant
  • Purity

    Tissue culture supernatant
  • Clonality

    Monoclonal
  • Clone number

    EPR5074
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab124896 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Detects a band of approximately 45 kDa (predicted molecular weight: 39 kDa).
IP 1/10 - 1/100.
IHC-P 1/100 - 1/250. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
  • Application notes
    Is unsuitable for Flow Cyt or ICC.
  • Target

    • Function

      Activator of CDK5/TPKII.
    • Tissue specificity

      Brain and neuron specific.
    • Sequence similarities

      Belongs to the cyclin-dependent kinase 5 activator family.
    • Information by UniProt
    • Database links

    • Alternative names

      • CD5R2_HUMAN antibody
      • CDK5 activator 2 antibody
      • Cdk5r2 antibody
      • Cyclin dependent kinase 5 activator 2 antibody
      • Cyclin dependent kinase 5 activator isoform p39i antibody
      • Cyclin dependent kinase 5 regulatory subunit 2 antibody
      • Cyclin-dependent kinase 5 activator 2 antibody
      • Cyclin-dependent kinase 5 regulatory subunit 2 antibody
      • NCK5AI antibody
      • Neuronal CDK5 activator isoform antibody
      • p39 antibody
      • P39I antibody
      • p39nck5ai antibody
      see all

    Images

    • ab124896, at 1/100 dilution, staining p39 in Paraffin-embedded Human Brain tissue by Immunohistochemistry.
    • All lanes : Anti-p39 antibody [EPR5074] (ab124896) at 1/1000 dilution

      Lane 1 : Human fetal brain lysate
      Lane 2 : SH-SY5Y lysate
      Lane 3 : Mouse brain lysate
      Lane 4 : Rat brain lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      All lanes : Goat anti-Rabbit HRP at 1/2000 dilution

      Predicted band size: 39 kDa

    References

    This product has been referenced in:

    • Pérez-Morales J  et al. Hyper-phosphorylation of Rb S249 together with CDK5R2/p39 overexpression are associated with impaired cell adhesion and epithelial-to-mesenchymal transition: Implications as a potential lung cancer grading and staging biomarker. PLoS One 13:e0207483 (2018). Read more (PubMed: 30452490) »
    See 1 Publication for this product

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab124896.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com

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