Overview

  • Product name

  • Description

    Rabbit polyclonal to p40-phox
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Rabbit
  • Immunogen

    Recombinant full length protein corresponding to Human p40-phox.
    Database link: Q15080

  • Positive control

    • WB: Jurkat, Raji, K562 and THP-1 whole cell lysates.
  • General notes

    Previously labelled as NCF4. 

Properties

Applications

Our Abpromise guarantee covers the use of ab227495 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 39 kDa.

Target

  • Function

    Component of the NADPH-oxidase, a multicomponent enzyme system responsible for the oxidative burst in which electrons are transported from NADPH to molecular oxygen, generating reactive oxidant intermediates. It may be important for the assembly and/or activation of the NADPH-oxidase complex.
  • Tissue specificity

    Expression is restricted to hematopoietic cells.
  • Sequence similarities

    Contains 1 PX (phox homology) domain.
    Contains 1 SH3 domain.
  • Cellular localization

    Cytoplasm.
  • Information by UniProt
  • Database links

  • Alternative names

    • CGD3 antibody
    • MGC3810 antibody
    • NCF 4 antibody
    • NCF antibody
    • NCF-4 antibody
    • Ncf4 antibody
    • NCF4_HUMAN antibody
    • Neutrophil cytosol factor 4 antibody
    • Neutrophil cytosolic factor 4 antibody
    • Neutrophil NADPH oxidase factor 4 antibody
    • p40-phox antibody
    • p40phox antibody
    • SH3 and PX domain-containing protein 4 antibody
    • SH3PXD4 antibody
    see all

Images

  • All lanes : Anti-p40-phox antibody (ab227495) at 1/1000 dilution

    Lane 1 : Jurkat (human T cell leukemia cell line from peripheral blood) whole cell lysate
    Lane 2 : Raji (human Burkitt's lymphoma cell line) whole cell lysate
    Lane 3 : K562 (human chronic myelogenous leukemia cell line from bone marrow) whole cell lysate
    Lane 4 : THP-1 (human monocytic leukemia cell line) whole cell lysate

    Lysates/proteins at 30 µg per lane.

    Predicted band size: 39 kDa



    10% SDS-PAGE gel.

References

ab227495 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab227495.
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