Overview

  • Product name

    Anti-P4HA3 antibody - N-terminal
    See all P4HA3 primary antibodies
  • Description

    Rabbit polyclonal to P4HA3 - N-terminal
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat, Horse, Guinea pig, Cow, Cat, Dog, Pig
  • Immunogen

    Synthetic peptide corresponding to a region within N-terminal amino acids 77-126 of Human P4HA3 (NP_878907).

  • Positive control

    • A549 cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab139567 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Detects a band of approximately 60 kDa (predicted molecular weight: 61 kDa).

Target

  • Function

    Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
  • Tissue specificity

    Highly expressed in placenta, liver and fetal skin. Weakly expressed in fetal epiphyseal cartilage, fetal liver, fibroblast, lung and skeletal muscle. Expressed also in fibrous cap of carotid atherosclerotic lesions.
  • Sequence similarities

    Belongs to the P4HA family.
    Contains 1 Fe2OG dioxygenase domain.
    Contains 1 TPR repeat.
  • Post-translational
    modifications

    N-glycosylation plays no role in the catalytic activity.
  • Cellular localization

    Endoplasmic reticulum lumen.
  • Information by UniProt
  • Database links

  • Alternative names

    • 2-oxoglutarate-4-dioxygenase subunit alpha-3 antibody
    • 4-PH alpha-3 antibody
    • P4ha3 antibody
    • P4HA3_HUMAN antibody
    • Procollagen-proline antibody
    • Procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide III antibody
    • Procollagen-proline, 2-oxoglutarate 4-dioxygenase, alpha subunit, isoform 3 antibody
    • Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-3 antibody
    • Prolyl 4-hydroxylase subunit alpha-3 antibody
    • Prolyl 4-hydroxylase, alpha polypeptide III antibody
    • Prolyl 4-hydroxylase, alpha-3 subunit antibody
    see all

Images

References

ab139567 has not yet been referenced specifically in any publications.

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