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ab8105 has been referenced in 21 publications.

  • Chen J  et al. Overexpression of p53R2 is associated with poor prognosis in lung sarcomatoid carcinoma. BMC Cancer 17:855 (2017). PubMed: 29246119
  • Narayanaswamy PB  et al. Transcriptomic pathway analysis of urokinase receptor silenced breast cancer cells: a microarray study. Oncotarget 8:101572-101590 (2017). PubMed: 29254187
  • Kuny CV & Kalejta RF Human Cytomegalovirus Can Procure Deoxyribonucleotides for Viral DNA Replication in the Absence of Retinoblastoma Protein Phosphorylation. J Virol 90:8634-43 (2016). PubMed: 27440891
  • Cilli P  et al. Oxidized dNTPs and the OGG1 and MUTYH DNA glycosylases combine to induce CAG/CTG repeat instability. Nucleic Acids Res 44:5190-203 (2016). WB . PubMed: 26980281
  • Marthandan S  et al. Conserved Senescence Associated Genes and Pathways in Primary Human Fibroblasts Detected by RNA-Seq. PLoS One 11:e0154531 (2016). WB . PubMed: 27140416
  • Tebbi A  et al. Caspase-dependent Proteolysis of Human Ribonucleotide Reductase Small Subunits R2 and p53R2 during Apoptosis. J Biol Chem 290:14077-90 (2015). PubMed: 25878246
  • Specks J  et al. A Single Conserved Residue Mediates Binding of the Ribonucleotide Reductase Catalytic Subunit RRM1 to RRM2 and Is Essential for Mouse Development. Mol Cell Biol 35:2910-7 (2015). PubMed: 26077802
  • Graindorge D  et al. Singlet Oxygen-Mediated Oxidation during UVA Radiation Alters the Dynamic of Genomic DNA Replication. PLoS One 10:e0140645 (2015). WB ; Human . PubMed: 26485711
  • Morgenroth A  et al. Breaking the invulnerability of cancer stem cells: two-step strategy to kill the stem-like cell subpopulation of multiple myeloma. Mol Cancer Ther 13:144-53 (2014). PubMed: 24174494
  • Allouch A  et al. p21-mediated RNR2 repression restricts HIV-1 replication in macrophages by inhibiting dNTP biosynthesis pathway. Proc Natl Acad Sci U S A 110:E3997-4006 (2013). PubMed: 24082141
  • Chandra S  et al. Enhancement of c-Myc degradation by BLM helicase leads to delayed tumor initiation. J Cell Sci 126:3782-95 (2013). PubMed: 23750012
  • Kunos C  et al. Ribonucleotide reductase inhibition restores platinum-sensitivity in platinum-resistant ovarian cancer: a Gynecologic Oncology Group Study. J Transl Med 10:79 (2012). IHC-P ; Human . PubMed: 22541066
  • Pontarin G  et al. Deoxyribonucleotide Metabolism in Cycling and Resting Human Fibroblasts with a Missense Mutation in p53R2, a Subunit of Ribonucleotide Reductase. J Biol Chem 286:11132-40 (2011). WB ; Human . PubMed: 21297166
  • Pitceathly RD  et al. Kearns-Sayre syndrome caused by defective R1/p53R2 assembly. J Med Genet : (2011). WB ; Human . PubMed: 21378381
  • Fyrberg A & Lotfi K Optimization and evaluation of electroporation delivery of siRNA in the human leukemic CEM cell line. Cytotechnology 62:497-507 (2010). PubMed: 20957432
  • Tyynismaa H  et al. A heterozygous truncating mutation in RRM2B causes autosomal-dominant progressive external ophthalmoplegia with multiple mtDNA deletions. Am J Hum Genet 85:290-5 (2009). PubMed: 19664747
  • Park JY  et al. p53 improves aerobic exercise capacity and augments skeletal muscle mitochondrial DNA content. Circ Res 105:705-12, 11 p following 712 (2009). WB ; Mouse . PubMed: 19696408
  • Pontarin G  et al. Ribonucleotide reduction is a cytosolic process in mammalian cells independently of DNA damage. Proc Natl Acad Sci U S A 105:17801-6 (2008). WB, ICC/IF ; Human . PubMed: 18997010
  • Bourdon A  et al. Mutation of RRM2B, encoding p53-controlled ribonucleotide reductase (p53R2), causes severe mitochondrial DNA depletion. Nat Genet 39:776-80 (2007). PubMed: 17486094
  • Pontarin G  et al. p53R2-dependent ribonucleotide reduction provides deoxyribonucleotides in quiescent human fibroblasts in the absence of induced DNA damage. J Biol Chem 282:16820-8 (2007). PubMed: 17416930
  • Mansson E  et al. Down-regulation of deoxycytidine kinase in human leukemic cell lines resistant to cladribine and clofarabine and increased ribonucleotide reductase activity contributes to fludarabine resistance. Biochem Pharmacol 65:237-47 (2003). PubMed: 12504799


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