Key features and details
- Mouse monoclonal [4A4, 34] to p63 Protein + HMW Cytokeratin
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG1
Product nameAnti-p63 Protein + HMW Cytokeratin antibody [4A4, 34]
DescriptionMouse monoclonal [4A4, 34] to p63 Protein + HMW Cytokeratin
Tested applicationsSuitable for: IHC-Pmore details
Species reactivityReacts with: Human
Recombinant human p63 protein (aa 1-205) and cytokeratin extract of human stratum corneum
- Normal prostate tissue or skin
General notesab58514 isotypes: IgG2a + IgG1
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferpH: 7.30
Preservative: 0.09% Sodium azide
Concentration information loading...
Clone number4A4, 34
Our Abpromise guarantee covers the use of ab58514 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
RelevanceThe p63 and high molecular weight cytokeratin cocktail is a marker for basal cells. The p63 protein, a homologue of the tumour-suppressor p53, is highly expressed in the nuclei of basal or progenitor layer of many epithelial tissues. p63 is detected in prostate basal cells in normal prostate glands and PIN. Other markers for basal cells are high molecular cytokeratins (CK 1, 5, 10 and 14). The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells.
Cellular localizationCytoplasmic and Nuclear
- CK13 antibody
- CK14 antibody
- CK15 antibody
ab58514 has not yet been referenced specifically in any publications.